18F-FDGPET／CT诊断腹膜转移瘤的临床价值

目的评价18F-脱氧葡萄糖（FDG）PET／CT在腹膜转移瘤诊断中的临床价值。方法回顾性分析22例有原发恶性肿瘤手术史或不明原因腹腔积液而临床高度怀疑腹膜转移的患者资料。所有病例均行18F—FDGPET／CT检查，经病理检查或临床随访证实。结果22例中，有18例18F-FDGPET／CT诊断阳性，其中16例确诊腹膜转移，2例确诊为腹腔结核；4例PET／CT诊断阴性，其中3例确诊为腹膜炎性病变，1例确诊为腹膜转移瘤。18F—FDGPET／CT诊断腹膜转移瘤的灵敏度为94．1％（16／17），特异性为3／5，阳性预测值为88．9％（16／18），阴性预测值为3／4，准确性为86．4％（18／22）。结论在诊断腹膜转移瘤方面，18F—FDGPET／CT是一种可靠的、准确性较高的无创性检查，有重要的临床应用价值。

The clinical role of ~(18)F-FDG PET/CT in diagnosis of the peritoneal carcinomatosis

Objective To evaluate the clinical role of ~(18)F-fluorodeoxyglucose (FDG) PET/CT in diagnosis of the peritoneal carcinomatosis.Methods The ~(18)F-FDG PET/CT scan was performed in 22 pa-tients.All had documented malignancy and had ascites.Histopathology or clinical follow-up was " gold standard" for diagnostic accuracy in PET/CT scan.Results Of these 22 patients, 18 had positive ~(18)F-FDG PET/CT findings.Sixteen were peritoneal carcinomatosis and 2 were peritoneal tuberculosis.Four pa-tients had negative ~(18)F-FDG PET/CT findings.Three were peritonitis and 1 was peritoneal carcinomatosis.The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of ~(18)F-FDG PET / CT in diagnosing peritoneal carcinomatosis were 94.1% (16/17), 3/5, 88.9% (16/18), 3/4, and 86.4% (19/22).Conclusions ~(18)F-FDG PET/CT had high sensitivity in detecting peritoneal carcinomato-sis.The most common false positive for ~(18)F-FDG PET/CT in ascites was peritoneal tuberculosis.