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软组织肉瘤手术加术中放疗的临床研究
引用本文:张宗春,高国香,刘松龄,郝代均,杨敬磊,黄显玉.软组织肉瘤手术加术中放疗的临床研究[J].中华肿瘤防治杂志,2007,14(23):1821-1822.
作者姓名:张宗春  高国香  刘松龄  郝代均  杨敬磊  黄显玉
作者单位:青岛市肿瘤医院放疗科,山东,青岛,266042
摘    要:目的:探讨软组织肉瘤术中放疗的意义。方法:对39例软组织肉瘤患者行根治或姑息性手术,术中放疗在术中放疗手术室进行,术中根据肿瘤大小,选择不同术中放疗限光筒及6~12MeV电子线1次照射15~25Gy,姑息手术者剂量加大至36Gy。术后辅以外照射治疗,常规设野,5/周,2Gy/次,总量40~50Gy。初发病灶10例,术后复发29例。结果:39例患者随访12~64个月,3、5年局控率分别为71.8%和64.1%。3年生存率为82.0%。结论:术中放疗具有较高的局控率,比之其他治疗具有许多优点,将获得较高的生存率。

关 键 词:肉瘤/外科学  肉瘤/放射疗法  软组织肿瘤
文章编号:1673-5269(2007)23-1821-02
修稿时间:2007年5月12日

Clinicai study of surgical treatment combined with intraoperative radiotherapy for the patients with soft tissue sarcomas
ZHANG Zong-chun,GAO Guo-xiang,LIU Song-ling,HAO Dai-jun,YANG Jing-lei,HUANG Xian-yu.Clinicai study of surgical treatment combined with intraoperative radiotherapy for the patients with soft tissue sarcomas[J].Chinese Journal of Cancer Prevention and Treatment,2007,14(23):1821-1822.
Authors:ZHANG Zong-chun  GAO Guo-xiang  LIU Song-ling  HAO Dai-jun  YANG Jing-lei  HUANG Xian-yu
Abstract:OBJECTIVE:To explore the value of intraoperative radiotherapy(IORT)for patients with soft tissue sarcomas.METHODS:Definitive IORT in combination with surgical excision was performed in 39 patients with soft tissue sarcoma(15-25 Gy),followed by additional postoperative external beam radiotherapy(40-50 Gy).There were 10 primary tumor and 29 recurrence.RESULTS:The follow-up was 12-64 months.3-,5-year local control were 71.8% and 64.1%,respectively.3-year overall survival was 82.0%.CONCLUSION:IORT combined with morderate dose of EBRT yields high local control and overall survival.
Keywords:sarcoma/surgery  sarcoma/radiotherapy  soft tissue neoplasms
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