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医用聚氨酯材料人工食管重建的组织再生观察
引用本文:沈冰,孙磊,江华,郎振为,王鹏,滕晓英,周新刚,张亮,王天佑.医用聚氨酯材料人工食管重建的组织再生观察[J].临床与实验病理学杂志,2011,27(10).
作者姓名:沈冰  孙磊  江华  郎振为  王鹏  滕晓英  周新刚  张亮  王天佑
作者单位:1. 首都医科大学附属北京地坛医院病理科,北京,100015
2. 山东大学附属省立医院胸外科,济南,250021
3. 首都医科大学附属北京友谊医院胸外科,100050
摘    要:目的 观察医用聚氨酯材料人工食管重建时的组织再生情况,探讨其重建犬颈段食管缺损的可行性.方法 纤维内镜观察人工食管及吻合口肉芽生长情况,并定期处死实验犬,取新生食管标本,进行肉眼及HE染色,镜下观察组织再生情况.结果 术后食管黏膜上皮细胞可再生,3个月可覆盖缺损部位;术后1~6个月未发现食管腺体、平滑肌和横纹肌的再生;人工食管脱落后,不宜在原位时间过长,以减少对黏膜的损伤.结论 医用聚氨酯材料构建的人工食管可以用于食管缺损重建,食管黏膜上皮可以再生.

关 键 词:人工食管  食管重建  聚氨酯

The tissue regeneration of reconstruction with artificial esophagus made of medical polyurethane
SHEN Bing,SUN Lei,JIANG Hua,LANG Zhen-wei,WANG Peng,TENG Xiao-ying,ZHOU Xin-gang,ZHANG Liang,WANG Tian-you.The tissue regeneration of reconstruction with artificial esophagus made of medical polyurethane[J].Chinese Journal of Clinical and Experimental Pathology,2011,27(10).
Authors:SHEN Bing  SUN Lei  JIANG Hua  LANG Zhen-wei  WANG Peng  TENG Xiao-ying  ZHOU Xin-gang  ZHANG Liang  WANG Tian-you
Institution:SHEN Bing1,SUN Lei1,JIANG Hua2,LANG Zhen-wei1,WANG Peng1,TENG Xiao-ying1,ZHOU Xin-gang1,ZHANG Liang1,WANG Tian-you3(1Department of Pathology,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China,2 Department of Thoracic Surgery,Shandong Provincial Hospital,Shandong University,Jinan 250021,3Department of Thoracic Surgery,Beijing Youyi Hospital,Beijing 100050,China)
Abstract:Purpose To observe the tissue regeneration of reconstruction with artificial esophagus made of medical polyurethane,and to study the feasibility of the new artificial esophagus in reconstruction of the cervical esophageal defect in a dog model.Methods Electric flexible esophagography was used to observe the artificial esophagus and granulation tissue,Gross and HE staining were used to observe regeneration of the esophageal tissues.Results The esophageal epithelium can regenerate,and it can cover the surface...
Keywords:artificial esophagus  esophageal reconstruction  polyurethane  
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