天津市海河医院结核合并2型糖尿病病例资料流行病学分析

目的了解结核合并2型糖尿病（TB—T2DM）流行病学情况，为制定相关的防治策略提供科学依据。方法统计分析天津市海河医院预防科2007—2010年TB登记资料。结果2007—2010年TB—T2DM患者227例，占同期登记TB患者比例4年平均为8．69％，平均年登记率为0．47／10万，4年间无明显的上升或下降趋势。男性TB—T2DM患者占TB登记人数中男性患者的构成比为8．28％，女性TB—T2DM患者构成比为9．51％，差异无统计学意义（x2=1．102，P〉O．05）。TB—T2DM患者年龄22～89岁，以中老年患者为主，40岁后两病并发率大幅上升。在TB—T2DM患者中，痰涂阳性者137例（60．35％）、涂阴77例（33．92％），出现空洞43例（18．94％）。TB—T2DM患者的涂阳率（x2=72．648，P〈0．01）和空洞率（x2=35．266，P〈0．01）均高于无合并T2DM的TB患者。结论TB—T2DM发生率较高，以中老年发病为主，涂阳率和空洞率均较高，给结核病控制带来一定的困难，所以要加强这一人群的防治工作。

Epidemiological Analysis of Tuberculosis Patients Complicated with Type 2 Diabetes Mellitus in Tianjin Haihe Hospital

Objective To understand epidemiological analysis of tuberculosis patients complicated with type 2 diabetes mellitus(TB-T2DM)in Tianjin Haihe Hospital.Methods The registration materials of TB-T2DM patients recorded from 2007 to 2010 in prevention division of Tianjin Haihe Hospital were analyzed.Results The total number of TB-T2DM patients were 227 from 2007 to 2010,accounted for 8.69% of total TB patients.The average annual registration rate was 0.47/100 000 and there was no obvious rise or decline trend during these 4 years.TB-T2DM proportion of the male accounted for 8.28% and the female for 9.51%,and there was no significant difference between gender(χ2=1.102,P>0.05).The age of TB-T2DM patients ranged from 22 to 89 years,majority was in middle-aged and elderly patients aged over 40 years old.Among TB-T2DM patients,137(60.35%)cases were smear positive,77 cases were smear negative(33.92%),while 43 cases were with cavity(18.94%).All these proportions were significantly higher than those in TB patients without diabetes(χ2=72.648,P<0.01 and χ2=35.266,P<0.01).Conclusion The TB-T2DM incidence is relatively high,and it mainly occurred in middle-aged and elderly cases.The proportions of both smear positive and with cavity were high.Therefore it is needed to strengthen TB control work in this population.