| miR-299-3p通过调控PAX3基因表达介导乳腺癌细胞增殖和凋亡 |
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| 引用本文： | 陈飞,李甜,王建东,刘晖,郑洁,王凤,姜姝君,胡俊艳,李喆.miR-299-3p通过调控PAX3基因表达介导乳腺癌细胞增殖和凋亡[J].中国现代普通外科进展,2022(1):1-6. |
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| 作者姓名： | 陈飞 李甜 王建东 刘晖 郑洁 王凤 姜姝君 胡俊艳 李喆 |
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| 作者单位： | 上海中医药大学附属曙光医院乳腺外科;上海中医药大学附属曙光医院宝山分院乳腺外科 |
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| 基金项目： | 上海市卫生和计划生育委员会中医药科研课题项目(2018LP036)。 |
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| 摘 要： | 目的:研究miR-299-3p对乳腺癌细胞增殖、凋亡的影响和潜在的分子机制.方法:以乳腺上皮细胞MCF-10A为对照,qRT-PCR检测乳腺癌MDA-MB-231和MDA-MB-468细胞中miR-299-3p和PAX3 mRNA的表达,Western blot检测MDA-MB-231和MDA-MB-468细胞中PAX...
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| 关 键 词： | 乳腺肿瘤 MDA-MB-231细胞 miR-299-3p PAX3 增殖 凋亡 |
miR-299-3p mediates the proliferation and apoptosis of breast cancer cells by regulating the expression of PAX3 gene |
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| CHEN Fei,LI.miR-299-3p mediates the proliferation and apoptosis of breast cancer cells by regulating the expression of PAX3 gene[J].Chinese Journal of Current Advances in General Surgery,2022(1):1-6. |
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| Authors: | CHEN Fei LI |
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| Institution: | (Department of Breast Surgery,Shuguang Hospital Affliated to Shanghai University Traditional Chinese Medicine,Shanghai 201203,China;Department of Breast Surgery,Baoshan Branch of Shuguang Hospital Affliated to Shanghai University Traditional Chinese Medicine,Shanghai 201999,China) |
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| Abstract: | |
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| Keywords: | Breast neoplasms MDA-MB-231 cells miR-299-3p PAX3 Proliferation Apoptosis |
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