非肌层浸润性膀胱癌患者经尿道膀胱肿瘤电切术治疗后复发的现状及其危险因素分析

目的 分析非肌层浸润性膀胱癌(NMIBC)患者经尿道膀胱肿瘤电切术治疗后复发的现状及其危险因素.方法 选取2017年1月至2019年1月于山西焦煤汾西矿业总医院泌尿外科接受择期经尿道膀胱肿瘤电切术治疗的NMIBC患者130例的临床资料,根据患者术后2年是否复发可分为复发组(27例)、无复发组(103例).根据山西焦煤汾...

Recurrence of non-muscle invasive bladder cancer and risk factors in patients after transurethral resec-tion of bladder tumor

Objective To investigate the recurrence of non-muscle invasive bladder cancer(NMIBC)and risk factors in patients after transurethral resection of bladder tumor(TURBT).Methods A retrospective study was conducted for clinical data from 130 NMIBC patients who underwent elective TURBT at Department of Urolo-gy,Shanxi Coking Coal Fenxi Mining Industry General Hospital between January 2017 and January 2019.De-pending on tumor recurrence at two years after surgery,the patients were divided into the recurrence group(n=27)and the non-recurrence group(n=103).The clinical data of the two groups were retrieved from the electronic med-ical record system of our hospital.Univariate analysis was performed,in which,resultant factors that showed sta-tistical significance were included in the multivariate analysis.Multivariate logistic regression analysis was used to determine the risk factors for recurrence after TURBT in NMIBC patients.Results Multivariate logistic regres-sion analysis showed that a TNM stagingof T1 tumor(OR=3.062),multiple lesions(OR=3.086,P<0.05),tumor size<5 cm(OR=3.380,P<0.05),medium to high differentiation by tumor grading(OR=2.815,P<0.05),and naivety to immediate bladder perfusion after surgery(OR=2.881,P<0.05)were independent risk factors for tumor recur-rence in NMIBC patients after TURBT.Conclusion The tumor recurrence in NMIBC patients after TURBT is closely related to the TNM staging,number of lesions,tumor size,tumor grading,and use of immediate bladder perfusion after surgery.Depending on these,clinical interventions can be timely given to reduce the tumor recur-rence in patients after surgery,and thereby to improve patient prognosis.