肝硬化食管静脉曲张患者硬化与套扎治疗对食管动力的影响

研究肝硬化门脉高压合并食管静脉曲张患者行硬化、套扎治疗对食管测压的影响。硬化与套扎治疗组均于治疗前及治疗后各测压一次，结果显示：（1）硬化剂治疗后，食管下端括约肌（LES）息压及松弛压力降低，松弛率升高，松弛持续时间缩短；套扎治疗仅对LES静息压有影响。（2）硬化剂治疗使治疗部位及其以下食管的蠕动波幅值下降，蠕动持续时间延长，蠕动波速度加快；套扎治疗使治疗部位及其以下食管的蠕动持续时间缩短，异常蠕动性收缩增加。提示经治疗后应使用既能降低胃酸酸碱度，又能增加LES压力的抗酸药物，而套扎治疗后应使用胃动力药物。

EFFECTS OF SCLEROTHERAPY AND BAND LIGATION ON THE ESOPHAGEAL MOTILITY IN ESOPHAGEAL VARICES DUE TO HEPATIC CIRRHOSIS

To evaluate the influences of sclerotherapy and band ligation on esophageal motility, EVS and EVL were measured before and after treatment respectively. After sclerotherapy, lower esophageal sphincter pressure (LESP)and residual pressure were decreased while relaxa tion was increased , relaxation duration became shorter; band ligation only influenced LESP.After EVS, the amplitude of motor waves in the sites of EVS and lower esophagus body was reduced ,and peristaltic wave duration was prolonged ,velocity of propagating contractions became faster , band ligation made the peristaltic wave duration in the sites of EVS and lower esophagus body become shorter, abnormal contractions increased. After EVS, antiacid medicine should be ased to reduced pH of gastric and raised LESP, and drugs to increase esophageal motility should be used after band ligation.