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mPGES-1 expression in non-cancerous liver tissue impacts on postoperative recurrence of HCC |
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| Authors: | Nonaka Koichi Fujioka Hikaru Takii Yasushi Abiru Seigo Migita Kiyoshi Ito Masahiro Kanematsu Takashi Ishibashi Hiromi |
| Affiliation: | Clinical Research Center and Department of Surgery, National Hospital Organization Nagasaki Medical Center, 2-1001-1 Kubara, Omura 856-8652, Japan. kknonaka@mbn.nifty.com |
| Abstract: | AIM:To investigate whether microsomal prostaglandin E synthase-1 (mPGES-1) expression in hepatocellular carcinoma (HCC) and in non-cancerous liver affects HCC prognosis after hepatectomy. METHODS: The relationship between patient clinical prof iles, tumor factors, surgical determinants, and mPGES-1 expression and the recurrence-free survival rate were examined in 64 patients who underwent curative hepatectomy between March 2003 and December 2006. RESULTS: The scores for mPGES-1 expression were higher in wel... |
| Keywords: | Curative resection Hepatocellular carcinoma Microsomal prostaglandin E synthase-1 Non-cancerous liver tissue Recurrence-free survival |
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