探讨红细胞分布宽度与自身免疫性肝炎的关系

目的分析红细胞分布宽度(RDW)与自身免疫性肝炎(AIH)严重程度的相互关系。方法选取本院2016年4月—2018年2月收治的50例AIH患者,将其设为AIH组;并选择同期收治的50例健康体检者和50例肝炎患者,分别将其设为健康对照组、疾病对照组;对三组研究对象的RDW水平进行检测。结果AIH组的RDW水平显著高于疾病对照组、健康对照组,比较差异有统计学意义(P<0.05);在AIH组中,Child-pugh分级为A级患者的RDW水平显著低于B、C级患者,比较差异有统计学意义(P<0.05)。对全部50例AIH组患者进行随访,26例患者病情缓解,24例患者病情复发;复发组的RAD水平显著低于缓解组,比较差异有统计学意义(P<0.05)。结论通过检测RDW水平能对AIH严重程度进行准确评估。

To Investigate the Relationship Between Erythrocyte Distribution Width(RDW)and the Severity of Autoimmune Hepatitis(AIH)

Objective To analyze the correlation between erythrocyte distribution width(RDW)and the severity of autoimmune hepatitis(AIH).Methods 50 AIH patients admitted to our hospital from April 2016 to February 2018 were selected and set as AIH group.In addition,50 healthy subjects and 50 hepatitis patients admitted to the hospital during the same period were selected as healthy control group and disease control group respectively.RDW levels of the three groups of subjects were tested.Results RDW level in AIH group was significantly higher than that in disease control group and healthy control group,and the difference was statistically significant(P<0.05).In AIH group,the RDW level of patients with Child-pugh grade A was significantly lower than that of patients with grade B and C,and the difference was statistically significant(P<0.05).All 50 patients in AIH group were followed up,26 patients were in remission,and 24 patients were in relapse.The RAD level in the relapse group was significantly lower than that in the remission group,and the difference was statistically significant(P<0.05).Conclusion The severity of AIH can be accurately evaluated by detecting the level of RDW.