PS联合CPAP治疗新生儿呼吸窘迫综合征临床研究

目的通过研究肺表面活性物质(PS)结合持续气道正压通气(CPAP)治疗新生儿呼吸窘迫综合征(NRDS)的治疗效果,进一步指导NRDS的临床治疗。方法选取于2017年4月-2018年10月间在本院收治的80例确诊为新生儿呼吸窘迫综合征的患儿作为研究对象,随机将患儿分为试验组和对照组,对照组给予持续气道正压通气治疗,试验组在对照组的基础上联合使用PS治疗。结果试验组对于呼吸窘迫缓解的有效率明显高于对照组,在气管插管内滴入PS治疗后试验组的血气情况明显优于对照组,且试验组患儿副作用发生率明显低于对照组,以上指标差异具有统计学意义,P <0.05。结论 PS结合CPAP在新生儿呼吸窘迫综合征的治疗中疗效很好。

Clinical Study of PS Combined With CPAP in the Treatment of Neonatal Respiratory Distress Syndrome

Objective To further guide the clinical treatment of NRDS by studying the therapeutic effect of pulmonary surfactant(PS) combined with continuous positive airway pressure(CPAP) in the treatment of neonatal respiratory distress syndrome(NRDS). Methods A total of 80 children diagnosed with neonatal respiratory distress syndrome admitted to our hospital from April 2017 to October 2018 were enrolled. The patients were randomly divided into experimental group and control group. Positive airway pressure therapy, the experimental group combined with PS treatment based on the control group. Results The effective rate of the experimental group for the relief of respiratory distress was significantly higher than that of the control group. After instilling PS into the endotracheal tube, the blood gas of the experimental group was significantly better than the control group, and the incidence of side effects in the experimental group was significantly lower than the control group The difference between the above indicators is statistically significant, P<0.05. Conclusion PS combined with CPAP is very effective in the treatment of neonatal respiratory distress syndrome, and should be promoted in clinical practice.