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分化型甲状腺癌术后循环肿瘤细胞检测与刺激性甲状腺球蛋白相关性的研究
引用本文:张富强,智建潮,李德宇,丁献敏,杨光,杨辉.分化型甲状腺癌术后循环肿瘤细胞检测与刺激性甲状腺球蛋白相关性的研究[J].临床医学工程,2021(2):155-156.
作者姓名:张富强  智建潮  李德宇  丁献敏  杨光  杨辉
作者单位:1.郑州大学附属肿瘤医院/河南省肿瘤医院核医学科;2.河南省虞城县人民医院肿瘤科
基金项目:河南省医学科技攻关计划联合共建项目“分化型甲状腺癌肿瘤循环细胞检测与Tg的相关性研究”(项目编号:LHGJ20190663)。
摘    要:目的探讨分化型甲状腺癌术后CTCs检测与s Tg之间的相关性。方法回顾性分析131例分化型甲状腺癌患者的临床资料,分析CTCs检测阳性率、CTCs检测结果和sTg浓度的相关性。结果CTCs检测阳性率为73.3%。CTCs检测结果与sTg浓度呈显著正相关(r=0.418,P<0.01)。结论CTCs检测结果与sTg浓度呈显著正相关,能准确预测分化型甲状腺癌早期转移。

关 键 词:分化型甲状腺癌  刺激性甲状腺球蛋白  循环肿瘤细胞

Correlation Between the Detection of Circulating Tumor Cells and Stimulating Thyroglobulin in Patients with Differentiated Thyroid Carcinoma After Surgery
ZHANG Fuqiang,ZHI Jianchao,LI Deyu,DING Xianmin,YANG Guang,YANG Hui.Correlation Between the Detection of Circulating Tumor Cells and Stimulating Thyroglobulin in Patients with Differentiated Thyroid Carcinoma After Surgery[J].Medical and Health Care Instruments,2021(2):155-156.
Authors:ZHANG Fuqiang  ZHI Jianchao  LI Deyu  DING Xianmin  YANG Guang  YANG Hui
Institution:(Department of Nuclear Medicine,the Affiliated Cancer Hospital of Zhengzhou University/He'nan Cancer Hospital,Zhengzhou 450003,China;Department of Oncology,Yucheng County People's Hospital,Shangqiu 476300,China)
Abstract:Objective To explore the correlation between CTCs detection and s Tg in patients with differentiated thyroid carcinoma after surgery.Methods The clinical data of 131 patients with differentiated thyroid carcinoma were retrospectively analyzed.The positive rate of CTCs detection,and the correlation between the results of CTCs detection and s Tg concentration was analyzed.Results The positive rate of CTCs detection was 73.3%.CTCs detection result was significantly positively correlated with s Tg concentration(r=0.418,P<0.01).Conclusions CTCs detection result is significantly positively correlated with s Tg concentration,which can accurately predict the early metastasis of differentiated thyroid carcinoma.
Keywords:Differentiated thyroid carcinoma  sTg  CTCs
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