Fault Detection and Safety in Closed-Loop Artificial Pancreas Systems |
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Authors: | B. Wayne Bequette |
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Affiliation: | 1.Rensselaer Polytechnic Institute, Troy, NY, USA |
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Abstract: | Continuous subcutaneous insulin infusion pumps and continuous glucose monitors enable individuals with type 1 diabetes to achieve tighter blood glucose control and are critical components in a closed-loop artificial pancreas. Insulin infusion sets can fail and continuous glucose monitor sensor signals can suffer from a variety of anomalies, including signal dropout and pressure-induced sensor attenuations. In addition to hardware-based failures, software and human-induced errors can cause safety-related problems. Techniques for fault detection, safety analyses, and remote monitoring techniques that have been applied in other industries and applications, such as chemical process plants and commercial aircraft, are discussed and placed in the context of a closed-loop artificial pancreas. |
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Keywords: | algorithms artificial pancreas fault detection infusion set failure sensor anomaly safety |
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