Kidney After Intestinal Transplantation Using Two Different Living Donors: A First Case Report |
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Affiliation: | 1. Department of Pediatrics, Second Affiliated Hospital of Jiaxing University, Jiaxing, ZJ, China;2. Department of Pathology and Molecular Medicine Center, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing University, Jiaxing, ZJ, China;1. Ege University Faculty of Medicine, Department of Cardiology, Izmir, Turkey;2. Doctor Ersin Arslan Training and Research Hospital, Department of Cardiology, Gaziantep, Turkey;3. Near East University Faculty of Medicine, Department of Cardiology, Cyprus;4. Ege University Faculty of Medicine, Department of Cardiovascular Surgery, Izmir, Turkey;5. Ege University Faculty of Medicine, Department of Internal Medicine, Izmir, Turkey;1. Department of General and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland;2. Foundation of Research and Science Development, Warsaw, Poland;3. Department of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw, Poland;1. Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea;2. Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, South Korea;3. School of Computer Science and Engineering, Soongsil University, Seoul, South Korea;4. Division of Liver Transplantation and Hepatobiliary Surgery, Departments of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea;1. Ataturk University, Medical Faculty, Department of Neurosurgery, Erzurum, Turkey;2. Ankara Higher Education and Research Hospital, Department of Cardiology, Ankara, Turkey;3. Uskudar University, Medical Faculty, Department of Psychiatri, Erzurum, Turkey;4. Ataturk University, Medical Faculty, Department of Anesthesiology and Reanimation, Erzurum, Turkey;5. Ataturk Training and Research Hospital, Department of Pathology Ankara, Turkey;6. Ataturk University, Medical Faculty, Department of Pathology, Erzurum, Turkey;1. Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada;2. Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada;3. Division of Cardiac Surgery, University of British Columbia, Vancouver, British Columbia, Canada |
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Abstract: | We describe a unique case of a 53-year-old woman who underwent a nonrelated living donor kidney transplant 9 years after a previous small bowel transplant from her sister. The patient had suffered from short bowel syndrome secondary to volvulus after undergoing bariatric surgery for morbid obesity. Her entire small bowel had to be resected emergently, but she also developed acute kidney failure at the time. This initial kidney injury associated with long-term exposure to calcineurin-inhibitor medication eventually led to end-stage renal disease. A successful kidney transplant from a different, nonrelated adult donor was performed. Of note, the unrelated kidney donor matched exactly the 2 HLA-A and HLA-B antigens that the recipient had not matched with her sister. We discuss the unique HLA configuration between the patient and her 2 living donors, the absence of posttransplant rejection and posttransplant immunosuppressive therapy. To our knowledge this is the first published report of a successful kidney after a previous bowel transplant using (2 different) living donors. |
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