ICL-V4c植入对人工晶状体度数计算的影响

目的：观察中央孔型有晶状体眼后房型人工晶状体ICL-V4c植入对人工晶状体（IOL）度数计算的影响。方法：前瞻性临床研究。选取2020年12月至2021年6月在新疆军区总医院北京路医疗区行ICL-V4c植入术并符合本研究纳排标准的患者40例（80眼），在术前及术后1d、1周、1个月、3个月使用IOLMaster500测量每例患者角膜屈光度、眼轴、前房深度（ACD），并通过SRK-T、HolladayⅠ、Haigis、Hoffer-Q公式计算得出IOL度数。采用重复测量方差分析进行数据分析。结果：角膜屈光度（K1、K2）术前及术后各时间点测量值之间的差异有统计学意义（F=34.23，P<0.001；F=14.64，P<0.001）。K1术后各时间点测量值均明显小于术前测量值（均P<0.001），术后各时间点测量值呈逐渐上升趋势；K2术后1d、1周、1个月、3个月测量值均明显大于术前测量值（均P<0.05），术后各时间点测量值呈逐渐降低趋势。ACD在术前及术后各时间点测量值之间的差异有统计学意义（F=36.90，P<0.001），术后各时间点测量值均明显小于术前测量值（均P<0.001），术后各时间点测量值之间两两比较差异均无统计学意义，呈平稳趋势。眼轴在术前及术后各时间点测量值之间的差异无统计学意义，各时间点测量值两两比较差异均无统计学意义。使用SRK-T、HolladayⅠ、Haigis、Hoffer-Q 公式计算获得的IOL度数在术前及术后各时间点的差异无统计学意义（均P>0.05）。结论：角膜屈光度及ACD的测量可能受ICL-V4c植入的影响，IOLMaster500通过SRK-T、HolladayⅠ、Haigis、Hoffer-Q公式计算IOL度数不受ICL-V4c的植入的影响。

Study on the Influence of ICL-V4c Implantation on Intraocular Lens Power Calculation

Objective: To evaluate the influence of posterior chamber intraocular lens ICL-V4c implantation on the intraocular lens (IOL) power calculation. Methods: This was a prospective clinical study. Forty patients (80 eyes) who underwent ICL-V4c implantations in Beijing Road medical District of General Hospital of Xinjiang military Region between December 2020 and June 2021. The IOL-Master 500 biometer was used to measure axial length (AL), keratometry (K1, K2), and anterior chamber depth (ACD) before and 1 day, 1 week, 1 month, 3 months after ICL-V4c implantation. The IOL power was calculated using SRK-T, Holladay , Haigis and Hoffer-Q formulas. Repeated measures ANOVA was used to analyze the data. Results: There was significant difference between the preoperative and postoperative keratometry (K1, K2) (F=34.23, P<0.001; F=14.64, P<0.001). The K1 after the operation were decreased significantly than preoperation (all P<0.001), and showed a gradual uptrend. The K2 after the operation were increased significantly than preoperation (all P<0.05), and showed a gradual downtrend. There was significant difference between the preoperative and postoperative ACD (F=36.90, P<0.001). ACD after the operation were decreased significantly than preoperation (all P<0.001). But there was no significant difference between follow up times after operation, and tended to be stable after operation. There was no significant difference between the preoperative and postoperative AL. The AL at each time point was no significantly difference. The IOL power calculation using SRK-T, Holladay , Haigis and Hoffer-Q formulas without significant differences between pre and postoperation. Conclusions: The results of this study suggest that the measurement of keratometry (K1, K2) and ACD may be affected by ICL-V4c implantation. But, the IOL power calculation using SRK-T, Holladay , Haigis and Hoffer-Q formulas did not change significantly after ICL-V4c implantation.