湖北省HIV/AIDS接受抗病毒治疗情况及其影响因素分析

目的 分析湖北省HIV感染者/AIDS患者(简称HIV/AIDS)接受抗病毒治疗情况及其影响因素。方法 通过中国疾病预防控制信息系统收集截至2020年底湖北省HIV/AIDS的随访治疗信息，描述其人口学特征，利用Logistic回归分析其接受抗病毒治疗的影响因素。结果 截至2020年底，湖北省HIV/AIDS抗病毒治疗比例为92.96%。多因素分析结果显示，性别、年龄、文化程度、婚姻状况、报告地区类别、确诊时长、感染途径，以及基线CD4不同的患者，其不接受抗病毒治疗的风险差异有统计学意义(P<0.05)。其中女性不治疗风险是男性的0.67倍；年龄≤70岁组不治疗风险是<30岁组的2.11倍；文化程度中专/高中和大专以上者不治疗风险分别是初中及以下文化程度者的0.75倍和0.55倍；单身患者不治疗风险是在婚患者的2.14倍；外省和本省其他地市报告者不治疗风险分别是本县区报告者的1.50倍和1.43倍；确诊时长5～<10年、10～<15年、≥15年者不治疗风险分别是确诊时长<5年者的0.71倍、0.51倍和0.32倍；吸毒途径传播和异性性传播途径感染者不治疗风...

Antiretroviral therapy and its influencing factors in HIV/AIDS patients in Hubei

Objective To analyze the status and influencing factors of antiretroviral therapy in HIV/AIDS patients in Hubei Province. Methods Follow-up treatment information of HIV/AIDS patients in Hubei province by the end of 2020 were collected through China Disease Control and Prevention Information System. Demographic characteristics were analyzed, and factors influencing treatment were analyzed by Logistic regression. Results By the end of 2020, the proportion of antiretroviral therapy of HIV/AIDS patients in Hubei was 92.96%. Multivariate analysis showed that there were differences in the risk of not being on treatment (NOT) among patients with different gender, age, education background, marriage status, reporting district type, length of time after diagnosis, route of infection, and baseline CD4 cell count (P<0.05). The risk of NOT among female was 0.67 times than that of male. The risk of NOT among ≥70 years old group was 2.11 times than that of group less than 30 years old. The risk of NOT among person with education background of senior high school and college and above was 0.75 times and 0.55 times than that of junior high school and below, respectively. The risk of NOT among being single was 2.14 times than that of being married. The risk of NOT among person reporting from other provinces and other cities in the province was 1.50 times and 1.43 times than that of reporting from the county, respectively. The risk of NOT after 5-<10, 10-<15 and ≥15 years of diagnosis was 0.71, 0.51 and 0.32 times than that of less than 5 years of diagnosis, respectively. The risk of NOT among person from intravenous and heterosexual transmission was 6.38 and 1.52 times than that of homosexual transmission, respectively. The risk of NOT among person with baseline CD4 counts of 200-<350, 350-<500,≥500 /mm³ and undetected was 1.68, 2.93, 3.92, and 171.98 times than that with baseline CD4 counts of less than 200/mm³, respectively. Conclusions The proportion of antiretroviral therapy for HIV/AIDS in Hubei province is affected by many factors, and targeted treatment mobilization measures should be taken according to the different characteristics of HIV/AIDS patients.