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EB病毒相关胃癌潜伏感染膜蛋白-1表达的研究
引用本文:李淑英,高金兰,夏庆安,周天戟. EB病毒相关胃癌潜伏感染膜蛋白-1表达的研究[J]. 华北煤炭医学院学报, 2006, 8(4): 435-436
作者姓名:李淑英  高金兰  夏庆安  周天戟
作者单位:1. 华北煤炭医学院生物科学系病原生物学科,河北,唐山,063000
2. 河北省遵化市水质检验所
3. 唐山工人医院
摘    要:①目的探讨EB病毒阳性胃癌(EBVaGC)中潜伏感染膜蛋白-1(LMP-1)的表达状况。②方法原位杂交法检测胃癌患者石蜡包埋组织标本中EB病毒编码的小RNA(EBV encoded RNA,166bps,EBER-1);免疫组化法检测EBVaGC中LMP-1。③结果EBVaGC中无LMP-1表达。④结论EB病毒阳性胃癌中缺乏潜伏感染膜蛋白LMP1的表达。

关 键 词:EB病毒  胃肿瘤  免疫组化  潜伏感染膜蛋白-1
文章编号:1008-6633(2006)04-0435-02
收稿时间:2006-01-26
修稿时间:2006-01-26

Study on the expression of LMP1 in EBV -associated gastric carcinoma
LI Shuying, GAO jinlan, XIA Qingan,et al. Study on the expression of LMP1 in EBV -associated gastric carcinoma[J]. Journal of North China Coal Medical College, 2006, 8(4): 435-436
Authors:LI Shuying   GAO jinlan   XIA Qingan  et al
Abstract:Objective To detect the expression LMP - 1 in EBV - associated gastric carcinoma. Methods EBER1 in 217 cases of gastric carcinoma were detected with In Situ Hybridization. EBV positive were selected to analyse the level of LMP - 1 by immunohistochemistry. Results The expression of LMP - 1 in EBVaGC were not detected. Conclusions EBVaGC Lost the expression of LMP - 1.
Keywords:EBV. Gastric carcinoma. Immunohistochemistry. LMP - 1
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