降钙素原对扩张性心肌病并感染的诊断意义

目的：探讨降钙素原在扩张性心肌病合并感染患者中的诊断价值。方法回顾性分析我院近年来收治的71例扩张性心肌病患者的临床资料,将合并感染的患者定为感染组,其余患者作为对照组,检测入院治疗前后患者血清降钙素原的水平。结果62例患者治疗好转出院,9例患者死亡,死亡率14.52%；感染组患者在入院后降钙素原水平（11.37±3.17）ng/ mL 显著高于对照组（0.29±0.18）ng/ mL；抗生素治疗后恢复期感染组降钙素原水平大幅度下降（0.30±0.26）ng/ mL,与对照组（0.28±0.19）ng/ mL 相比差异无统计学意义；血清降钙素原诊断扩张性心肌病合并感染的灵敏度为89.47%,特异度为90.90%。结论血清降钙素原可以作为扩张性心肌病合并感染较为理想的诊断及治疗效果评估标志物。

The diagnostic value of procalcitonin in patients withdilated cardiomyopathy complicated infection

Objective To investigate the diagnostic value of procalcitonin in patients with dilated cardiomyopathy complicated infection. Methods The clinical data of 71 patients with dilated cardiomyopathy were retrospectively studied in our hospital. The 71 patients were classified into infection group and the rest of the patients as control group. The serum level of procalcitonin was detected. Results Of the patients, 9 cases died and the mortality rate was 14. 52% . The procalcitonin level in infected group was significantly higher than the control group before treatment （11. 37 ± 3. 17）ng/ mL versus （0. 29 ± 0. 18）ng/ mL. After treatment the procalcitonin level in the infection group dramatically dropped, with no significant difference to the control group （0. 30 ± 0. 26）ng/ mL versus（0. 28 ± 0. 19）ng/ mL. The sensitivity and specificity of serum procalcitonin in diagnosing dilated cardiomyopathy combined infection was 89. 47% and 90. 90% , respectively. Conclusion Serum procalcitonin can be used as an ideal marker in the diagnosis and treatment of dilated cardiomyopathy combined with infection.