| 基质细胞衍生因子-1(SDF-1)表达与复发性流产的关系 |
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| 引用本文： | 徐楗荧,杨桂艳,刘彦,鹿榕.基质细胞衍生因子-1(SDF-1)表达与复发性流产的关系[J].生殖与避孕,2014(6):511-514. |
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| 作者姓名： | 徐楗荧 杨桂艳 刘彦 鹿榕 |
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| 作者单位： | [1]珠海市妇幼保健院生殖中心,珠海519000 [2]珠海市第二人民医院妇产科,珠海519000 [3]珠海市妇幼保健院妇产科,珠海519000 |
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| 摘 要： | 目的:探讨复发性流产(recurrent spontaneous abortions,RSA)患者血清及滋养细胞中基质细胞衍生因子-1(stromal cell-derived factor 1,SDF-1)表达与流产的关系。方法:应用酶联免疫吸附试验及荧光定量聚合酶链反应方法检测RSA患者血清及绒毛组织中SDF-1 mRNA的表达(n=36),同期选取因非意愿妊娠7~9周行人工流产患者的血清及绒毛(n=36)作为对照组。结果:RSA患者血清及滋养细胞中SDF-1蛋白及mRNA的表达均显著低于正常妊娠者,差异有统计学意义(P0.01)。结论:RSA患者SDF-1蛋白及mRNA低表达与流产发生关系密切。
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| 关 键 词： | 基质细胞衍生因子-1(SDF-1) 复发性流产(RSA) 绒毛 滋养细胞 |
Relationship between the Expression of Stromal Cell-derived Factor 1 （SDF-1） and Recurrent Spontaneous Abortions |
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| Jian-ying XU,Gui-yan YANG,Yan LIU,Rong LU.Relationship between the Expression of Stromal Cell-derived Factor 1 （SDF-1） and Recurrent Spontaneous Abortions[J].Reproduction and Contraception,2014(6):511-514. |
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| Authors: | Jian-ying XU Gui-yan YANG Yan LIU Rong LU |
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| Institution: | 1. Reproductive center, Zhuhai Maternal and Children＇s Hospital and Health Institute, Zhuhai 519000;2. Department of Obstetrics and Gynecology, the Second People Hospital of Zhuhai, Zhuhai, 519000;3. Department of Obstetrics and Gynecology, Zhuhai Maternal and Children ＇s Hospital and Health Institute, Zhuhai, 519000) |
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| Abstract: | |
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| Keywords: | stromal cell-derived factor 1 （SDF-1） recurrent spontaneous abortions （RSA） villi trophoblasts |
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