肝硬化腹膜炎患者血清及腹水降钙素原水平检测的意义

目的探讨肝硬化腹膜炎患者血清及腹水降钙素原(PCT)水平及其临床意义。方法选择71例肝硬化腹水患者,其中伴自发性细菌性腹膜炎(SBP)49例,非SBP22例,采用免疫透射比浊法测定其血清及腹水中PCT的含量,并与正常对照组比较。结果伴SBP组及非SBP组患者血清PCT水平明显高于正常对照组(P<0.01);伴SBP组血清PCT水平明显高于非SBP组(P<0.01);伴SBP组腹水PCT水平明显高于非SBP组(P<0.01);30例治疗有效的SBP患者血清及腹水PCT水平均明显下降,与其治疗前血清及腹水PCT水平比较有显著性差异(P<0.01)。结论检测血清及腹水降钙素原水平对于肝硬化腹膜炎的早期诊断及判断预后有一定临床价值。

Clinical significance of serum and ascites procalcitonin levels in liver cirrhotic patients with spontaneous bacterial peritonitis

Objective To study serum and ascites levels of procalcitonin(PCT) in liver cirrhotic patients with spontaneous bacterial peritonitis and their clinical significance.Methods The 71 cirrhotic patients with ascites were selected into this study among whom there were 49 patients with spontaneous bacterial peritonitis(SBP) and 22 without SBP.Serum and ascites levels of PCT were detected and compared with those of normal controls.Results Serum levels of PCT in patients with SBPand without SBP patients were significantly higher than those in normal controls(P<0.01); Serum levels of PCT in patients with SBP were significantly higher than those in patients without SBP(P<0.01); ascites levels of PCT in patients with SBP were significantly higher than those in patient without SBP (P<0.01).Conclusion The detection of serum and ascites levels of PCT has an important value in early diagnosis and judgement of prognosis of SBP in liver cirrhosis.