本院202例药品不良反应报告分析

目的：探讨本院药品不良反应（ADR）特点及相关因素,促进临床合理用药。方法：对从本院门诊药房退药记录中收集的202例ADR报告进行统计分析。结果：202例ADR中,静脉给药引起的ADR最多,占总例数的75.74%（153例）;与抗感染药物有关的ADR最为多见,占总例数的76.23%（154例）;中药制剂占总例数的10.89%（22例）;ADR表现以皮肤及附件损伤为主,占总例数的47.52%（96例）,其次是消化系统,较严重的ADR有7例（3.47%）。结论：应重视ADR监测工作,加强对抗感染药物的使用管理并重点监测,以避免或减少ADR发生。

Adverse drug reaction reports in our hospital: survey of 202 cases

AIM: To improve the rational drug use in clinic by discussing characteristics and related factors on adverse drug reactions (ADR) in our hospital. METHODS: Analyze the statistics of 202 ADR reports collected from the records of the returned drugs in outpatient pharmacies. RESULTS: Among 202 cases of ADR, the number of that ADR caused by intravenous injection was the largest which is 75.74% of the total number of cases (153 cases); ADR caused by infective drugs was the commonest, as 76.23% of the total number of cases (154 cases). Chinese medicines accounted for 10.89% of the total number of cases (22 cases). Main performances of ADR were injuries on skin and organ annexes, it was 47.52% of the total number of cases (96 cases). Follow that, the second most severe injury was on the digestive system, there were 7 more serious ADR (3.47%) in statistics. CONCLUSION: The monitoring on ADR should be paid more attention to. It is also necessary to strengthen the management of anti-infective drugs' use and focus on monitoring it to reduce the number of ADR among patients.