慢性青光眼患者不同程度视野缺损情况分析

目的:研究单眼视野已严重缺损的慢性青光眼患者对侧眼视野缺损情况,并分析其视野缺损的相关危险因素。方法:对47例单眼视野已严重缺损(视野缺损计分≥12分)的慢性青光眼患者[原发性慢性闭角型青光眼(primary chronic angle-closed glaucoma,PACG)23例和原发性开角型青光眼(primary openangle glaucoma,POAG)24例]的对侧眼视野进行视野缺损计分,分析对侧眼视力、最高眼压和平均眼压、年龄、屈光度、诊断、病程、性别及抗青光眼手术与否与对侧眼视野缺损计分的关系。应用Spearman相关分析分析上述因素与对侧眼视野缺损计分的相关性。结果:23例PACG患者中,对侧眼视野缺损情况为:无视野缺损者(计分为0分)4例,轻度视野缺损者(计分为1~5分)5例,中度视野缺损者(计分为6~11分)7例,严重视野缺损或终末期视野缺损者(计分为12~20分)7例。24例POAG患者中,对侧眼视野缺损情况为:轻度视野缺损者(计分为1~5分)4例,中度视野缺损者(计分为6~11分)9例,严重视野缺损或终末期视野缺损者(计分为12~20分)11例。PACG患者病程大于或等于10年...

The Analysis of Various Extent Visual Field Defect in Chronic Glaucoma Patients

PURPOSE: To study the situation for the follow eye visual field defect of patients with severe visual field loss in 1 eye from chronic glaucoma,and to analyze the relative risk factors for visual field defect in such eyes. METHODS: The visual field defect scores of fellow eyes were calculated in 47 cases [primary chronic angle-closed glaucoma (PACG) 23 cases and primary open angle glaucoma (POAG) 24 cases] with severe visual field loss in 1 eye (visual field defect score > or = 12). The relations were analyzed between the visual field defect scores of fellow eyes and the visual acuity,the maximal and the mean intraocular pressure (IOP), ages, refraction, diagnosis, the last periods of glaucoma, gender and the anti-glaucoma surgery history. Spearman correlation analyse was used to estimated the correlation between the visual field defect scores of fellow eyes and the above factors. RESULTS: In the fellow eyes of the 23 cases PACG, 4 cases showed no visual field defect (score 0),5 cases showed the mild visual field defect (score 1-5), 7 cases showed the moderate visual field defect (score 6-11), 7 cases showed the severe or end-stage visual field defect (score 12-20).In the fellow eyes of the 24 cases POAG, 4 cases showed the mild visual field defect (score 1-5), 9 cases showed the moderate visual field defect (score 6-11), 11 cases showed the severe or end-stage visual field defect (score 12-20). The visual field defect score of fellow eyes in the last periods more than or equal to 10 years PACG group was significantly larger than that in the last periods less than 10 years PACG group (Z=2.8380, P=0.0224). The visual field defect score of fellow eyes in the mean IOP more than 18 mmHg PACG group was significantly larger than that in the mean IOP less than or equal to 18 mmHg PACG group (Z=1.9174, P=0.0276). The visual field defect score of fellow eyes in the anti-glaucoma surgery history POAG group was significantly larger than that in the non-anti-glaucoma surgery history POAG group (Z= 2.2377, P=0.0252). The significant positive correlation was found between the visual field defect scores and the mean IOP of the fellow eyes in the PACG group (r=0.4763, P= 0.0216),and the significant negative correlation was found between the visual field defect score and the visual acuity of the fellow eyes in the PACG group (r=-0.4416, P= 0.0349). CONCLUSION: Among the PACG with severe visual field loss in 1 eye, the visual field defect extent in the fellow eyes was related to the mean IOP, the last periods of PACG and the visual acuity of the fellow eyes.The visual field defect score was positively correlated with the mean IOP, and negatively correlated with the visual acuity of the fellow eyes.