清毒汤治疗肝病肠源性内毒素症临床观察

目的:观察中药复方清毒汤治疗肝病肠源性内毒素症的疗效.方法:将60例重型肝炎、失代偿性肝硬化合并腹水、腹腔感染,内毒素检测阳性的患者,分为治疗组和对照组各30例.在综合治疗基础上治疗组加用清毒汤,对照组加用乳果糖,观察两组患者治疗前后鲎试验,症状等变化及对肝、肾功能的影响,并进行统计学分析.结果:清毒汤治疗慢性重型肝病肠源性内毒素症,可减少内毒素血症时间,快速缓解肠源性内毒素相关的发热、腹胀等症状,对抗内毒素所致肝损害,提高重型肝病好转率,显著优于对照组,在降低血氨方面也有较好作用.结论:中医药治疗肝病肠源性内毒素症安全、有效,值得进一步研究推广.

Clinical Study of Compound Formula Qingdutang on Intestinal Endotoxemia in Patients with Liver Disease

Objective:To study the curative effective of compound formula Qingdutang on intestinal endotoxemia in patients with liver disease. Methods:All the 60 patients met the criteria of severe hepatitis of decompensated liver cirrhosis with ascites and spontaneous bacterial peritonitis and entotoxin tests were positive. They were classified into therapy group and control group. Qingdutang was used in therapy. Results: Treatment by Qingdutang was conductive to shorten the time of endotoxemia, improve fever, dwell and other symptoms related to intestinal endotoxemia rapidly, and increase recovery rate of sever hepatitis. There was significant difference between the two groups. By the way, it suggested better effects in lowering blood amon. Conclusion: Treatment by traditional Chinese medicine on intestinal endotoxemia in patients with liver disease is safe and effective. It worthy be developing farther.