Evoked potentials in multiple system atrophy (MSA) |
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Authors: | Abele M Schulz J B Bürk K Topka H Dichgans J Klockgether T |
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Institution: | Department of Neurology, University of Tübingen, Germany. |
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Abstract: | OBJECTIVES: To study the involvement of pyramidal tracts and sensory pathways in multiple system atrophy (MSA). MATERIALS AND METHODS: Evoked potential studies were performed in 45 MSA patients suffering from either MSA of cerebellar type (MSA-C) or MSA of parkinsonian type (MSA-P). RESULTS: Motor evoked potentials were normal in all MSA patients, whereas visual and somatosensory evoked potential abnormalities were found in about 40% of the MSA patients with no significant difference between the cerebellar (MSA-C) and parkinsonian (MSA-P) subgroup. Abnormal latencies of wave III in brainstem auditory evoked potentials were significantly more frequent in MSA-C. CONCLUSIONS: Abnormalities of somatosensory, visual and auditory evoked potentials are frequent findings in MSA, whereas abnormal motor evoked potentials are not a characteristic feature of the disease. |
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Keywords: | multiple system atrophy visual evoked potentials motor evoked potentials somatosensory evoked potentials brainstem auditory evoked potentials |
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