广东地区肺癌多原发癌46例的外科疗效和预后分析

目的:探讨广东地区肺癌多原发癌(MPC)的诊治及其预后因素.方法:对1987-01/2003-09 中山大学肿瘤防治中心收治肺癌MPC 46例临床资料进行回顾性分析.结果:发生部位共97处,原发肺癌54处,头颈部28处,泌尿生殖系统7处,消化系统7处,其他1处,分别占55.7%, 28.9%, 7.2%, 7.2%和1.0% . 根治性手术组(CSR)与姑息治疗组(NCSR)的3 a生存率分别为74%和21%,差异有统计学意义(P=0.000).结论:肺癌MPC应尽可能行根治性手术.

Surgical outcome and prognosis factor analysis for multiple primary lung cancers in Guangdong province

AIM: To study the diagnosis, treatment and prognostic factors of multiple primary lung cancers in Guangdong province. METHODS: The clinical data of 46 cases of multiple primary lung cancers treated at cancer center of Sun Yat-Sen University from January 1987 to September 2003 were reviewed. RESULTS: Forty-six cases in this study had 97 malignant tumors, including lung cancer (n=54), head and neck cancer (n=28), urogenital system cancer (n=7), digestive system cancer 7, the other site 1. The incidents were 55.7%, 28.9%, 7.2%, 7.2% and 1.0% respectively. The 3-year survival rates were 74% and 21% respectively for the group of completely surgical resection and the group of non-completely surgical resection. The difference of survival rate was significant statistically (P=0.000). CONCLUSION: Radical operation is the first choice for the patients of multiple primary lung cancers.