| 紫外分光光度法测定复方甲硝唑栓的含量 |
| |
| 引用本文： | 吕莉君,刘福. 紫外分光光度法测定复方甲硝唑栓的含量[J]. 川北医学院学报, 2001, 16(4): 90-92 |
| |
| 作者姓名： | 吕莉君 刘福 |
| |
| 作者单位： | 1. 川北医学院校医院,
2. 川北医学院附属医院药剂科, |
| |
| 摘 要： | 目的 :测定复方甲硝唑栓的含量。方法 :采用差示分光光度法和单波长法 ,不经分离直接测定复方甲硝唑栓中甲硝唑和氯霉素的含量 ,测定波长为 2 78nm和 32 0nm。结果 :甲硝唑的平均回收率为 10 0 .0 3% ,RSD为 0 .85 % (n =5 ) ,氯霉素的平均回收率为 99.6 5 % ,RSD为 0 .5 3% (n =5 )。结论 :该法定量准确 ,快速 ,简便 ,可作为该制剂的含量测定及质量控制
|
| 关 键 词： | 差示分光光度法 单波长分光光度法 甲硝唑 氯霉素 |
| 文章编号： | 1005-3697(2001)04-0090-02 |
| 修稿时间： | 2001-05-09 |
Determination of compound metronidazole suppositories by ultraviolet sp ectrophotometry |
| |
| NU Li_jun ,LIU Fu. Determination of compound metronidazole suppositories by ultraviolet sp ectrophotometry[J]. Journal of North Sichuan Medical College, 2001, 16(4): 90-92 |
| |
| Authors: | NU Li_jun LIU Fu |
| |
| Affiliation: | NU Li_jun 1,LIU Fu 2 |
| |
| Abstract: | Aim:To assay the content of compound metronidazole suppositories. Methods: Compound metronidazole suppositories was analyzed directly without any separation by using differential spectrophotometry and single wavelength spectrophotometry in wavelength 278nm and 320nm. Results The average recoveries of metronidozole and chloramphenicol were 100.03%(RSD=0.85%)and 99.65%(RSD=0.53%)respectively. Conclusion The method for determination of preparation is accurate, rapid and simple. It could be used as quality control in the supposifories. |
| |
| Keywords: | differential spectrophotometry singl wavelength spectrophotometry metronidozole chloramphenicol. |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
