Pathology of human malignant gliomas after radiation and chemotherapy |
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| Authors: | D. Schiffer M. T. Giordana P. Paoletti R. Soffietti L. Tarenzi |
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| Affiliation: | (1) Present address: II Neurological Clinic, University of Torino, Torino, Italy;(2) Present address: Neurosurgical Clinic, University of Pavia, Pavia, Italy |
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| Abstract: | Summary The pathological effects of radio- and chemotherapy have been studied in 31 malignant gliomas. The brains have been examined by means of the complete study technique. Many histological features have been related to surgery, localization, preoperative duration, postoperative survival, irradiation, and chemotherapy. No specific alterations have been found, but some positive correlations have been established: decrease of mitoses, occurrence of macrophages and vessel degeneration after radiation, increase of monstrous cells after chemotherapy.This paper was presented in part at the Fall Meeting of BTSG (Brain Tumor Study Group) at the National Institutes of Health, Bethesda, Maryland, 7 December 1979.Supported in part by NIH Grant No. 1 CM 67056.We are greatly indebted to Mrs. Margherita Bessone Valsasna for skilful technical assistance. |
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| Keywords: | Malignant gliomas pathology radio chemotherapy |
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