解脲脲原体培养及耐药性分析

目的了解解脲脲原体（UU）耐药状况，指导临床合理用药。方法应用支原体微量培养及同步药敏系列试剂盒进行解脲脲原体检测及药敏分析。结果1991例疑似非淋菌性尿道炎（NGU）患者中853例阳性，阳性率42．8％。对环丙沙星、氧氟沙星耐药率最高，分别为76．2％和44．8％；其次是红霉素、克拉霉素和阿奇霉素，分别为17．1％、15．8％和10．7％；四环素、多西环索、交沙霉素和原始霉索耐药率最低，分别为6．O％、3．5％、0．6％和0．5％。结论临床治疗UU引起的非淋菌性尿道炎，推荐首选交沙霉素、多西环素、四环素。

Analysis of Ureaplasma urealyticum culture and drug susceptibility

Objective To acquire the information about the current resistance characteristics in Ureaplasma urealyticum(UU),and instruct rationale application of antibiotics clinically.Methods Series of mycoplasma microculture and synchronism drug-sensitivity test kits were used to identify the Ureaplasma urealyticum and analyze the drug susceptibility.Results Among 1991 cases of non-gonoccocal ureathritis(NGU),UU positive were 853 cases(42.8%).The result of susceptibility showed that the highest resistant rates to ciprofloxacin,ofloxacin were 76.2% and 44.8%,respectively,then,erythromycin,clarythromycin,azithromycin were 17.1%,15.8% and 10.7%,respectively,the lowest resistant rates was of tetracycline, doxycycline,josamycin and pristinamycin were 6.0%,3.5%,0.6% and 0.5%,respectivel.Conclusion Josamycin,doxycycline and tetracycline are recommended to be the first choice to treat NGU.