青年脑梗死患者血清尿素氮和短期预后关系

目的探讨入院时血尿素氮水平和脑梗死患者短期预后的关系,尤其是在青年脑梗死患者中的关系。方法选择613例青年脑梗死患者,他们出院时的预后采用modified Rankin Scale评分标准,应用logistic回归分析模型。结果预后较差的脑梗死患者,入院时血清尿素氮水平更多在较高的四分位数水平。Logistic回归分析证实青年脑梗死的独立危险因素是:尿素氮(OR=1.145;P<0.05)。结论入院时血清尿素氮水平预示着青年脑梗死患者出院时较差的短期预后。

Relationship between young patients with cerebral infarction and shortterm prognosis of urea nitrogen

Objective To study the relationship between of admission BUN levels and short-term outcome of young patients with cerebral infarction at discharge.Methods We selected 613 young Chinese adults with acute ischemic stroke as determined by the modified Rankin Scale at discharge using multivariate logistic regression modeling.Results Much higher admission BUN levels were more frequently in the higher quintile for patients with severe stroke.Patients caused by large-vessel blockage had higher BUN concentrations and the higher mRS scores,moreover,the highest BUN concentrations and the highest mRS scores were seen in patients with cardiogenic cerebral infarction.Logistic regression analysis adjusted for confounders confirmed the following independent predictors for young cerebral infarction:BUN(OR value=1.145,P=0.005).Conclusion BUN is an independent predictor for poor short-term outcome of young cerebral infarction at discharge.