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感特灵胶囊质量标准鉴别项下(1)(2)(3)方法的改进和西药成分半含量考察
引用本文:孙洪刚,柯颖,陈笑强,杨永田,卢刚,徐骞,贾首时,张杰. 感特灵胶囊质量标准鉴别项下(1)(2)(3)方法的改进和西药成分半含量考察[J]. 中国医药科学, 2011, 0(9): 46-47
作者姓名:孙洪刚  柯颖  陈笑强  杨永田  卢刚  徐骞  贾首时  张杰
作者单位:黑龙江省齐齐哈尔市第一医院;黑龙江省齐齐哈尔市药品检验所;齐齐哈尔医学院
摘    要:目的建立更好的感特灵胶囊的质量标准控制。方法采用薄层色谱法对制剂中的对乙酰氨基酚、咖啡因、马来酸氯苯那敏及人工牛黄进行定性鉴别和半含量考察。结果采用TLC法,一次展开系统,同时鉴别4种主药成分及其半含量考察,各主药成分的Rf值均在0.2~0.8之间,分离效果良好,样品溶液与对照品溶液所显斑点位置一致。结论薄层色谱法简便、准确、专属性好,在抗感冒类药物的真伪鉴别及质量快速筛查上可用性很高。

关 键 词:感特灵胶囊  TLC  质量标准

Ganteling Capsule Quality Standard Identification Captioned (1)(2)(3) Method Improvement and Western Medicine Composition Half Content Inspection
SUN Honggang,KE Ying,CHEN Xiaoqiang,YANG Yongtian,LU Gang,XU Qian,JIA Shoushi,ZHANG Jie. Ganteling Capsule Quality Standard Identification Captioned (1)(2)(3) Method Improvement and Western Medicine Composition Half Content Inspection[J]. China Medicine and Pharmacy, 2011, 0(9): 46-47
Authors:SUN Honggang  KE Ying  CHEN Xiaoqiang  YANG Yongtian  LU Gang  XU Qian  JIA Shoushi  ZHANG Jie
Affiliation:1.First Hospital of Qiqihar City,Heilongjiang Province,Qiqihar 161005,China;2.Drug Inspection Offices,Qiqihar City,Heilongjiang Province,Qiqihar 161006,China;3.Qiqihar Medical School,Qiqihar 161006,China
Abstract:Objective To establish a quality better standard for Ganteling capsule.Methods Maleate Tablets were distinguished by adopting TLC.Results By TLC method,once started the system,and identification of 4 main components and semi-content in drug investigation,the main drug component of the Rf values was between 0.2 to 0.8,good separation,the sample solution was spotted with the position of the reference solution consistent.Conclusion The method is simple and accurare and highly reproducible.It could be used for the quality control of Maleate Tablets.
Keywords:Ganteling Capsule  TLC  Quality standard
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