| 小鼠皮肤移植外周血T淋巴细胞形态变化研究 |
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| 引用本文： | 徐原,安兴,娄金丽,戴洁,刘志文,李宁.小鼠皮肤移植外周血T淋巴细胞形态变化研究[J].北京医学,2011,33(6):458-460. |
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| 作者姓名： | 徐原 安兴 娄金丽 戴洁 刘志文 李宁 |
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| 作者单位： | 首都医科大学附属北京佑安医院普通外科,100069;北京理工大学信号与图像处理研究室;北京肝病研究所分子生物学实验室;首都医科大学临床病理中心 |
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| 摘 要： | 目的 探究同种异系异体小鼠皮肤移植后外周血中T淋巴细胞形态变化与移植排斥程度之间的关系,以期为诊断排斥反应提供一种新的无创检测方法.方法 203只清洁级健康雄性Balb/c小鼠,随机分为3组:空白对照组、自体移植组、异体移植组.分别于术后各时相点断尾取外周血在超显微真彩细胞分析仪下观察,寻找T淋巴细胞并录像记录其变化...
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| 关 键 词： | T淋巴细胞形态 急性排斥反应 细胞显微成像 |
Morphologic changes of peripheral T-lymphocyte in skin transplantation on mice |
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| XU Yuan,AN Xing,LOU Jin-li,et al.Morphologic changes of peripheral T-lymphocyte in skin transplantation on mice[J].Beijing Medical Journal,2011,33(6):458-460. |
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| Authors: | XU Yuan AN Xing LOU Jin-li |
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| Institution: | XU Yuan,AN Xing,LOU Jin-li,et al(Department of General Surgery,Beijing You'An Hospital,Capital Medical University,Beijing 100069) |
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| Abstract: | Objective To study the morphologic changes of T-Lymphocyte of peripheral blood in rejection of skin transplantation on mice,and provide a new non-invasive detection method for the diagnosis of acute rejection.Methods Totally 203 male Balb/c mice were randomly distributed into 3 different groups:the blank control group,the self skin transplantation group,the allogenic skin transplantation group.In each group,the mice were divided into 14 points subgroups,and allocated 7 rats in each point.We acquired the per... |
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| Keywords: | Morphology of T-lymphocyte Acut rejection Cell microscopy |
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