FiltekTM Z350对犬龈沟液中天冬氨酸转氨酶和碱性磷酸酶的影响

目的:探讨纳米复合树脂FiltekTMZ350(Z350)和临床常用牙体充填材料Dyract-AP复合体(AP)、TPH复合树脂(TPH)、玻璃离子Ⅱ型水门汀(GIC)修复后,犬龈沟液中天冬氨酸转氨酶和碱性磷酸酶的变化,评价FiltekTM Z350作为修复材料对牙周组织健康的影响。方法:3只比格犬,每只选择20个健康牙作为实验牙,分别在颊侧颈部齐龈缘处制备相同大小的洞形后,按象限随机分为4组,分别用Z350、AP、TPH、GIC修复,在术前和术后7、30、90 d测量龈沟液(GCF)量,并检测龈沟液中天冬氨酸转氨酶(AST)和碱性磷酸酶(ALP)的水平。结果:修复后7 d其GCF量、GCF中AST和ALP总量较修复前明显增高,但各组间没有显著性差异(P>0.05);修复后30 d和90 d,GIC组GCF量、GCF中AST和ALP总量均高于其他材料组(P<0.05),FiltekTM Z350组GCF量、GCF中AST和ALP总量低于其他材料组(P<0.05)。结论:在本实验条件下,FiltekTMZ350纳米复合树脂对牙周组织健康的影响小于其他常用修复材料。

The effect of FiltekTM Z350 resin on aspartate aminotransferase and alkaline phosphatase concentrations in gingival crevicular fluid of Beagle dog

AIM: To investigate the influence of FiltekTM Z350 resin on the periodontium of Beagle dogs by terms of aspartate aminotransferase(AST) and alkaline phosphatase(ALP) concentration changes in gingival crevicular fluid(GCF).METHODS: Sixty healthy teeth from three adult male Beagle dogs were recruited in this study.Buccal Class V deep cavities were prepared,which were then divided into four groups at random.The cavities were filled with FiltekTM Z350 resin,Dyract AP compomer,TPH resin and glass ionomer cement(...