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23G玻璃体切除术治疗视网膜静脉阻塞黄斑水肿合并玻璃体黄斑牵拉或黄斑前膜
引用本文:郭省香,刘秋平,刘蓓,谢安明,秦莉,李晶明.23G玻璃体切除术治疗视网膜静脉阻塞黄斑水肿合并玻璃体黄斑牵拉或黄斑前膜[J].国际眼科杂志,2017,17(9):1685-1688.
作者姓名:郭省香  刘秋平  刘蓓  谢安明  秦莉  李晶明
作者单位:1. 710061 中国陕西省西安市,西安交通大学第一附属医院眼科;710018 中国陕西省西安市第三医院眼科;2. 南昌大学附属眼科医院, 中国江西省南昌市,330006;3. 710004,中国陕西省西安市第四医院眼科;4. 西安交通大学第一附属医院眼科, 中国陕西省西安市,710061
基金项目:国家自然科学基金项目(No.81460163、81400427、 81300786); 陕西省青年科技新星项目(No.2016KJXX-12); 陕西省自然科学基金项目(No.2016JM8029、2012JM4023); 西安交通大学基本科研业务费专项科研项目(No.1191320094); 教育部博士学科点基金(No.20133601120012); 江西省科技厅项目(No.20142BAB215029、20132BAB205024、20142BDH80005); 江西省教育厅科技项目(No.GJJ14094、GJJ13175)
摘    要:目的:探讨23G玻璃体手术治疗视网膜静脉阻塞黄斑水肿合并玻璃体黄斑牵拉或视网膜黄斑前膜的临床疗效.方法:对22例22眼视网膜静脉阻塞黄斑水肿合并玻璃体黄斑牵拉或黄斑前膜病例进行回顾性分析.其中12例12眼行23G玻璃体切除手术并剥离视网膜前膜和/或内界膜作为观察组即手术组;另外10例10眼未行手术患者作为对照组,并收集全部患者治疗前、治疗后1、3、6mo的最佳矫正视力(BCVA)及中央视网膜厚度(CRT)资料进行统计学分析.结果:观察组和对照组治疗前BCVA和CRT差异无统计学意义(P=0.645、0.206).观察组术后各随访时间点BCVA较术前均明显提高,差异有统计学意义(F=2.895,P=0.048);CRT较术前明显降低,差异均有统计学意义(F=16.431,P<0.01).对照组随访期内1、3、6mo BCVA及CRT较治疗前无明显改善,差异均无统计学意义.随访期3、6mo时,观察组BCVA较对照组提高,CRT较对照组时降低,差异均有统计学意义(P<0.05);而1mo时,观察组BCVA及CRT较对照组无明显改善.结论:23G玻璃体切割手术可以有效地提高视网膜静脉阻塞黄斑水肿合并玻璃体黄斑牵拉或黄斑前膜患者视力并降低中央视网膜厚度.

关 键 词:玻璃体黄斑牵拉  视网膜黄斑前膜  黄斑水肿  视网膜静脉阻塞  23G玻璃体切除术
收稿时间:2017/5/9 0:00:00
修稿时间:2017/7/31 0:00:00

23G vitrectomy outcomes of macular edema in retinal vein occlusion combined with vitreomacular traction or epiretinal membrane
Sheng-Xiang Guo,Qiu-Ping Liu,Bei Liu,An-Ming Xie,Li Qin and Jing-Ming Li.23G vitrectomy outcomes of macular edema in retinal vein occlusion combined with vitreomacular traction or epiretinal membrane[J].International Journal of Ophthalmology,2017,17(9):1685-1688.
Authors:Sheng-Xiang Guo  Qiu-Ping Liu  Bei Liu  An-Ming Xie  Li Qin and Jing-Ming Li
Institution:Department of Ophthalmology, First Affiliated Hospital of Xi''an Jiaotong University, Xi''an 710061, Shaanxi Province, China; Department of Ophthalmology, Xi''an No. 3 Hospital, Xi''an 710018, Shaanxi Province, China,Affiliated Eye Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China,Department of Ophthalmology, Xi''an No.4 Hospital, Xi''an 710004, Shaanxi Province, China*Co-first Author: Sheng-Xiang Guo and Qiu-Ping Liu.,Department of Ophthalmology, First Affiliated Hospital of Xi''an Jiaotong University, Xi''an 710061, Shaanxi Province, China,Department of Ophthalmology, First Affiliated Hospital of Xi''an Jiaotong University, Xi''an 710061, Shaanxi Province, China and Department of Ophthalmology, First Affiliated Hospital of Xi''an Jiaotong University, Xi''an 710061, Shaanxi Province, China
Abstract:AIM: To evaluate 23G vitrectomy for macular edema in eyes with retinal vein occlusion(RVO)combined with vitreoretinal traction(VMT)or epiretinal membrane(ERM).

METHODS: Totally 22 patients(22 eyes)diagnosed with macular edema of RVO combined with VMT or ERM were retrospectively analyzed. Twelve cases performed with 23G vitrectomy together with peeling of inner limiting membrane(ILM)and/or ERM were considered as the observation group or intervention group. Ten cases without vitrectomy were recruited as control group. The best corrected visual acuity(BCVA)and central retinal thickness(CRT)at baseline, 1, 3 and 6mo were recorded and compared.

RESULTS: At baseline, the difference of BCVA and CRT between observation group and control group was not statistically significant(P=0.645, 0.206). After vitrectomy, the BCVA and CRT of RVO patients in observation group were significantly improved compared with baseline at each follow-up(F=2.895, P=0.048; F=16.431, P<0.01). However, the BCVA and CRT in control group remained the same as baseline at every follow-up. Moreover, the BCVA and CRT in observation group were much better than that in control group at both 3 and 6mo after vitrectomy. However, the BCVA and CRT between two groups were not significantly different at 1mo postoperatively.

CONCLUSION: The 23G vitrectomy could markedly improve BCVA and reduce CRT in RVO patients with macular edema combined with VMT and/or ERM.

Keywords:vitreoretinal traction  epiretinal membrane  macular edema  retinal vein occlusion  23G vitrectomy
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