| 一体化PET/MR评估脑血流量的研究进展 |
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| 引用本文： | 单艺,卢洁,李坤成. 一体化PET/MR评估脑血流量的研究进展[J]. 中国医学影像技术, 2017, 33(8): 1269-1272 |
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| 作者姓名： | 单艺 卢洁 李坤成 |
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| 作者单位： | 首都医科大学宣武医院放射科 北京磁共振成像脑信息学北京市重点实验室, 北京 100053,首都医科大学宣武医院放射科 北京磁共振成像脑信息学北京市重点实验室, 北京 100053,首都医科大学宣武医院放射科 北京磁共振成像脑信息学北京市重点实验室, 北京 100053 |
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| 基金项目： | 国家自然科学基金面上项目（81671662）、国家重点研发计划项目（2016YFC0103001）、北京市医院管理局重点医学专业发展计划（ZYLX201609） |
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| 摘 要： | 一体化PET/MR技术具有一次扫描可同时获得PET和MRI图像的独特优势，目前已逐步应用于临床。准确定量分析脑血流量（CBF）对研究脑血管病、脑肿瘤、癫痫等脑部重大疾病的发病机制及临床转归具有重要价值。一体化PET/MR可实现无创、简便、准确获得动脉输入函数，从而精准定量CBF。本文对一体化PET/MR评估CBF的研究进展进行综述。
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| 关 键 词： | 磁共振成像 正电子发射体层摄影术 脑血流 |
| 收稿时间： | 2016-02-22 |
| 修稿时间： | 2017-06-10 |
Progresses of hybrid PET/MR in quantificative evaluation of cerebral blood flow |
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| SHAN Yi,LU Jie and LI Kuncheng. Progresses of hybrid PET/MR in quantificative evaluation of cerebral blood flow[J]. Chinese Journal of Medical Imaging Technology, 2017, 33(8): 1269-1272 |
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| Authors: | SHAN Yi LU Jie LI Kuncheng |
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| Affiliation: | Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China,Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China and Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing 100053, China |
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| Abstract: | The hybrid PET/MR has a unique advantage of simultaneous scanning of both PET and MRI images,which has been gradually applied in clinical practice.In the clinical studies of severe brain diseases (such as cerebrovascular disease,brain tumor and epilepsy),accurate quantification of cerebral blood flow (CBF) can help to understand the etiology,pathogenesis,and to make early diagnosis as well as therapeutic solutions.The hybrid PET/MR can implement a noninvasive,convenient and accurate method of arterial input function for quantification of CBF.The application of the hybrid PET/MR in quantification of cerebral blood flow were reviewed in this article. |
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| Keywords: | Magnetic resonance imaging Positron-emission tomography Cerebral blood flow |
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