瑞芬太尼与芬太尼在小儿先天性心脏病介入手术麻醉中的效果分析

目的 探讨瑞芬太尼与芬太尼在小儿先天性心脏病介入手术麻醉中的效果。方法 80例小儿先天性心脏病患儿入院后被分为两组，对照组（40例）给予芬太尼麻醉，观察组（40例）给予瑞芬太尼麻醉，依据麻醉前后不同时间的收缩压（SDP）、舒张压（DBP）、心率（HR），两种麻醉药物的拔管时间、苏醒时间及麻醉用药量及麻醉期间患儿出现的不良反应情况，评价瑞芬太尼与芬太尼在小儿先天性心脏病介入手术麻醉中的效果。结果 与诱导前的基础值相比，麻醉药物诱导后两组SDP、DBP值均降低，组内比较差异有统计学意义（P<0.05）；两组HR水平与诱导前的基础值相比，差异无统计学意义。观察组拔管时间、苏醒时间均短于对照组，组间差异有统计学意义（P<0.05）；但观察组麻醉药物用量多于对照组，两组比较差异显著（P<0.05）。麻醉期间，两组不良反应率相比，差异无统计学意义。结论 瑞芬太尼对小儿先天性心脏介入手术麻醉效果好，对心功能的影响较小，术后能早期拔管，副作用较小，是目前临床上一种理想的麻醉药物。

Anesthetic effect of remifentanil and fentanyl on interventional surgery for children with congenital heart disease

Objective Discuss the anesthetic effect of remifentanil and fentanyl on interventional surgery for children with congenital heart disease. Methods 80 patients with congenital heart disease were selected, they were divided into two groups randomly. The control group (40 cases) was given fentanyl anesthesia. The observation group (40 cases) was given remifentanil anesthesia. Observe and record SDP, DBP, HR at different time of anesthesia, extubation time, recovery time and dosage of anesthesia and adverse reaction during anesthesia to evaluate the anesthetic effect of remifentanil and fentanyl on interventional surgery for children with congenital heart disease. Results Compared with the basic value before induction of anesthesia, the SDP, DBP of two groups were decreased after induction (P<0.05). There was no significant difference on HR level between two groups before and after induction. The extubation time, recovery time of observation group was shorter than that of the control group. However, the amount of anesthesia drug in the observation group was higher than that of the control group (P<0.05). During anesthesia, there was no significant difference on adverse reactions between two groups. Conclusion The anesthetic effect of remifentanil on interventional surgery for children with congenital heart disease is good, and it has little effect on cardiac function with early extubation and less side effect.