非小细胞肺癌手术淋巴结的清扫数目与术后胸腔引流量及预后的相关性

目的：探讨非小细胞肺癌手术淋巴结清扫数目与术后胸腔引流量及预后的相关性。方法收集行开胸或胸腔镜肺叶切除并淋巴结清扫的非小细胞肺癌患者148例，并随机分为对照组（74例）和实验组（74例）。通过对比研究2组患者术中淋巴结清扫数目以及术后胸腔引流量的关系。结果2组患者在手术时间、术中出血量方面比较，差异具统计学意义（P＜0．05）；而在术后胸腔第1天引流量、术后胸腔总引流量、术后带管时间及术后住院时间上没有明显差异（ P＞0．05）。实验组清扫淋巴结总数多于对照组，两者差异具有统计学意义（ P＜0．05）。2组淋巴结转移率以及转移度比较无明显差异（P＞0．05）。实验组术后肿瘤复发率为7．69％，相比于对照组术后肿瘤复发率10．26％，差异具有统计学意义（P＜0．05）；实验组术后肿瘤的转移率为11．54％，相对于对照组肿瘤转移率16．67％，差异具有统计学意义（P＜0．05）。对照组和实验组患者在术后死亡率上差异没有统计学意义（P＞0．05）。结论非小细胞肺癌手术的淋巴结清扫数目与术后胸腔引流量无明确的相关性，但淋巴结清扫数目关系到患者的肿瘤转移和复发，对患者的预后有积极作用。

Correlation between Non-small Cell Lung Cancer Lymph Node Dissection Number and Postoperative Chest Drainage and Prognosis

Objective To investigate the correlation between non-small cell lung cancer lymph node dissection number and postoperative chest drainage and prognosis.Methods 148 cases of non-small cell lung cancer patients treated with thoracoto-my or VATS lobectomy and lymph node dissection were randomly divided into the control group (74 cases) and the experimental group (74 cases).Relationship between lymph node dissection number and postoperative chest drainage flow were compared.Re-sults Operative time and blood loss between the 2 groups had statistically significant difference (P<0.05);while the first day after chest drainage,postoperative chest total flow, postoperative tube time and hospital stay had no significant difference ( P>0.05).The total number of lymph node dissection in the experimental group was more than that of the control group,the differ-ence was statistically significant (P<0.05).There was no significant difference in the rate of lymph node metastasis and transfer rate of the control group (P>0.05).In the experimental group,tumor recurrence rate was 7.69%,compared with the control group 10.26%,the difference was statistically significant (P<0.05);in the experimental group,tumor metastasis rate was 11. 54%,compared to the control group 16.67%,the difference was statistically significant (P<0.05).There was no statistically significant difference between the 2 groups in the postoperative mortality (P>0.05).Conclusion Non-small cell lung cancer lymph node dissection number and postoperative chest drainage have no clear correlation,but lymph node dissection number is re-lated to tumor metastasis and recurrence of patients,the prognosis of patients have a positive effect.