肺癌根治性袖状切除术对非小细胞肺癌患者炎症因子及预后的影响

目的：研究肺癌根治性袖状切除术对非小细胞肺癌患者炎症因子及预后的影响。方法对60例非小细胞肺癌患者分别采用袖状切除术（观察组）和全肺切除术（对照组）进行治疗，比较2组患者的手术相关信息、术后并发症、术后1、3、5年生存率和手术前后炎症因子等差异。结果观察组在手术时间、手术中出血量和手术后住院时间方面都明显优于对照组，差异有统计学意义（P＜0．05）。在术后并发症发生率方面，观察组都明显少于对照组，差异有统计学意义（P＜0．05）。观察组术后1、3、5年生存率都比对照组高，差异有统计学意义（P＜0．05）。在患者手术前后炎症因子的比较中，2组差异不具有统计学意义（P＞0．05）。结论肺癌根治性袖状切除术治疗非小细胞肺癌，效果明显优于全肺切除术，且在对炎症因子的影响少。

Influence of Lung Radical Sleeve Resection on Inflammatory Factors and Prognosis of Patients with Non-small Cell Lung Cancer

Objective To study the influence of lung radical sleeve resection on inflammatory factors and prognosis of patients with non-small cell lung cancer.Methods 60 cases of non-small cell lung cancer patients respectively received sleeve resection ( observation group) and whole lung resection ( control group) .Surgery-related information,postoperative complications, postoperative 1-,3-,5-year survival rates and inflammatory factors were compared.Results Operative time,blood loss and length of hospital stay after surgery of the observation group was significantly better than those of the control group, the difference was statistically significant(P<0.05).The incidence of postoperative complications in the observation group were significantly less than that of the control group,the difference was statistically significant(P<0.05).1-,3-,5-year survival rate were higher than those of the control group,the difference was statistically significant(P<0.05).There had no difference between the 2 groups in inflammatory cytokines before and after surgery(P>0.05).Conclusion Lung radical sleeve resection for non-small cell lung cancer had better efficacy than the whole lung resection,and the influence on inflammatory factors is less.