经肝动脉化疗栓塞术联合射频消融治疗

近年来在原发性肝癌治疗领域中新兴治疗方法层出不穷，但由于病变多发生于进展期肝病或肝硬化的基础上，导致原发性肝癌仍然是一种难治性恶性肿瘤。外科手术切除及肝移植虽是根治性治疗方法，但由于移植相关问题的复杂性及原发性肝癌本身的隐匿性，使得上述两种治疗方法并不能适用于大多数患者。而近些年随着设备和技术水平的提高，原发性肝癌的介入治疗得到了越来越多的重视，这其中应用最为广泛的就是经肝动脉化疗栓塞术（TACE）和经皮肝穿刺射频消融（RFA）。主要讨论上述两种介入疗法联合应用治疗原发性肝癌的有效性、可行性，以及近年来介入治疗在原发性肝癌治疗领域的研究进展。

Current status of transcatheter arterial chemoembolization combined with radiofrequency ablation in treatment of primary liver cancer

In recent years,more and more therapeutic methods have been applied for the treatment of primary liver cancer;however,since most lesions develop from progressive liver disease or liver cirrhosis,primary liver cancer is still a refractory malignant tumor.Although sur-gical resection and liver transplantation are radical therapeutic methods,they are not applicable to most patients due to complex issues related to transplantation and insidious onset of such disease.With the improvement in equipment and technology,the interventional therapies for primary liver cancer have been taken more seriously,especially transcatheter arterial chemoembolization and percutaneous radiofrequency ab-lation.This article investigates the effect and feasibility of the combination of these two therapies for primary liver cancer and introduces the research advances in interventional therapy for primary liver cancer.