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非酒精性脂肪肝与肥胖及胰岛素抵抗关系的研究
引用本文:刘青,孟祥伟,孙中华,刘艳,迟宝荣. 非酒精性脂肪肝与肥胖及胰岛素抵抗关系的研究[J]. 吉林医学, 2003, 24(6): 507-508
作者姓名:刘青  孟祥伟  孙中华  刘艳  迟宝荣
作者单位:吉林大学第一医院内分泌科 吉林长春130021(刘青,孙中华,刘艳),吉林大学第一医院消化内科 吉林长春130021(孟祥伟),吉林大学第一医院消化内科 吉林长春130021(迟宝荣)
摘    要:目的:探讨非酒精性脂肪肝与肥胖、胰岛素抵抗之间的关系。方法:采用对照研究,对Ⅱ型糖尿病伴有脂肪肝(DF)组59例和Ⅱ型糖尿病不伴有脂肪肝(NDF)组43例患者,测定身高、体重、腰围(WI)、臀围,检测血糖、血脂和胰岛素,计算体重指数(BMI)、腰臀比(WHR)及胰岛素抵抗指数(HOMA-IR),进行统计学分析。结果:DF组的BMI、WI、WHR、总胆固醇(TC)、甘油三酯(TG)、空腹胰岛素(FINS)水平和HOMA-IR均明显高于NDF组(P<0.05)。结论:非酒精性脂肪肝的发生与肥胖、胰岛素抵抗密切相关。

关 键 词:非酒精性脂肪肝  肥胖  胰岛素抵抗
文章编号:1004-0412(2003)06-0507-02
修稿时间:2003-09-28

Association of nonalcoholic fatty liver disease with obesity and insulin resistance
LIU Qing ,MENG Xiang -wei ,SUN Zhong -hua ,et al.. Association of nonalcoholic fatty liver disease with obesity and insulin resistance[J]. Jilin Medical Journal, 2003, 24(6): 507-508
Authors:LIU Qing   MENG Xiang -wei   SUN Zhong -hua   et al.
Affiliation:LIU Qing 1,MENG Xiang -wei 2,SUN Zhong -hua 1,et al.
Abstract:Objective To study the relationship between nonalcoholic fatty liver disease (NAFLD),obesity and insulin resistance.Method High,weight,waist circumference(WI),hip circumference(HI),serum lipid,fasting and2-hour postprandial blood glucose and insulin were detected in59patients with typeⅡdiabetes accompanying fatty liver(DF),43patients with typeⅡdiabetes without fatty liver(NDF).Body mass index(BMI),waist-hip ratio(WHR)and insulin resistance index(HOMA-IR)were calculated.Data were statistically analyzed.Results The results showed that BMI,WI,WHR,TC,TG,fasting insulin(FINS)and HOMA-IR were signifi-cantly elevated in the subjects of DF,compared with those of NDF (P<0.05).Conclusion NAFLD were intimately associated with obesity and insulin resistance.
Keywords:NAFLD  Obesity  Insulin resistance
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