中长链脂肪酸食用油对不同年龄男性高甘油三酯血症患者血脂的影响

目的探讨中长链脂肪酸食用油对不同年龄男性高甘油三酯血症患者脂代谢的影响。方法按随机双盲对照的研究方法将67名男性高甘油三酯血症患者分为中长链脂肪酸食用油组和长链脂肪酸食用油组，控制每日食用油摄入量（20～30g／d），研究前后对两组研究对象进行人体成份测量及血生化指标检测。结果中长链脂肪酸食用油组≤60岁男性在研究8周后甘油三酯（TG）、胆固醇（TC）、载脂蛋白B（apoB）、载脂蛋白AⅠ（apoAⅠ）、载脂蛋白AⅡ（apoAⅡ）、载脂蛋白CⅡ（apoCⅡ）、载脂蛋白CⅢ（apoCⅢ）、载脂蛋白E（apoE）及低密度脂蛋白胆固醇（LDL—C）降低的程度均优于长链脂肪酸食用油组（P〈0．05）；〉60岁男性TC、apoAⅠ、apoB、apoCⅡ、apoCⅢ及LDL—C降低的程度均优于长链脂肪酸食用油组（P〈0．05）。结论合理膳食条件下。中长链脂肪酸食用油可不同程度改善高TG血症患者脂代谢．有利于动脉粥样硬化的预防．

Effects of Medium-and Long-chain Fatty Acid Triacylglycerol on Lipid Metabolism in Different Age'' s Male Subjects with Hypertriglyceridemia

Objective To investigate the effects of medium- and long-chain fatty acid triacylglycerols on lipid metabolism in different age＇s male subjects with hypertriglyceridemia. Methods A randomized double-blind and controlled clinical trial was carried out among 74 male cases with hypertriacylglycerolemia. They were divided into two groups, one group was randomized to taking long-chain fatty acid triacylglycerol oil （LCT）, and the other one to medium- and long-chain fatty acid triacylglycerol oil （MLCT）. All cases in two groups asked to consume 20-30 g oil daily. Anthropometric measurements and blood biochemical variables were measured at the initial and final time of the study. Results There were 34 and 33 cases left in LCT and MLCT group, respectively. A greater extent of decrease in the levels of blood TG, TC, apoB, apoA Ⅰ , apoAⅡ, apoCⅡ, apoC Ⅲ, apoE and LDL-C in male subjects aged less than 60 years was found in MLCT group than in LCT group after 8 weeks study （P〈0.05）. A greater extent of decrease in the levels of TC, apoA Ⅰ, apoB, apoC Ⅱ, apoC m and LDL-C in male subjects aged more than 60 years was found in MLCT group than in LCT group after 8 weeks （P〈0.05）. Conclusion Consumption of medium-and long-chain fatty acid triaeylglyeerol may help to improve apolipoprotein metabolism in different age male eases with hypertriacylglycemlemia by different extents under an appropriate dietary regime.