A Case of Cardiac Amyloidosis Presenting with Mid- to Late Diastolic Retrograde Flow from the Left Atrium to the Pulmonary Vein: Transesophageal Pulsed Doppler Echocardiographic Observations |
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Authors: | Oki Takashi Fukuda Nobuo Iuchi Arata Tabata Tomotsugu Manabe Kazuyo Kageji Yoshimi Sasaki Miwa Yamada Hirotsugu Ito Susumu |
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Institution: | The Second Department of Internal Medicine, Tokushima University School of Medicine, Tokushima, Japan |
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Abstract: | A patient of cardiac amyloidosis was found to have mid-to late diastolic retrograde flow from the left atrium (LA) to the pulmonary vein. Congo-red staining was positive for amyloid in the rectal tissue. M-mode and two-dimensional echocardiograms revealed symmetric hypertrophy and typical speckled pattern of the left ventricle (LV). The LV pressure curve showed a dip and plateau configuration during diastole, and end-diastolic pressure was 28 mmHg. In addition, the LV pressure was high at mid-diastole, surpassing the pulmonary capillary wedge pressure from mid-to late diastole. The transmitral flow velocity revealed "restrictive" pattern, and the pulmonary venous flow velocity showed retrograde flow from the LA to the pulmonary vein during mid-diastole and atrial systole. It is suggested that recording of the pulmonary venous flow velocity by transesophageal pulsed Doppler echocardiography is useful for understanding the mechanism of the development of pulmonary congestion or edema. |
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Keywords: | cardiac amyloidosis transesophageal pulsed Doppler echocardiography pulmonary venous retrograde flow left ventricular end-diastolic pressure |
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