炎琥宁联合硫代硫酸钠治疗湿疹的效果

目的：探讨炎琥宁联合硫代硫酸钠治疗湿疹的效果。方法随机将80例湿疹患者分为接受硫代硫酸钠治疗的对照组及接受炎琥宁联合硫代硫酸钠治疗的观察组，每组各40例。对比两组的临床疗效及药物副作用发生率。结果两组治疗前的临床症状计分、皮疹面积计分及临床症状总积分比较，差异无统计学意义（P〉0.05），治疗后，两组的上述评分均明显改善（P〈0.05），以观察组改善更为明显（P〈0.05）；观察组的皮疹消失及住院时间明显短于对照组（P〈0.05）；观察组的总有效率明显高于对照组（P〈0.05）；两组的药物副作用发生率比较，差异无统计学意义（P〉0.05）。结论炎琥宁联合硫代硫酸钠可显著改善治疗湿疹的效果，且不增高药物副作用发生率。

Effect of potassium sodium dehydroandroan drographolide succinate combined with sodium thiosulfate in the treatment of eczema

Objective To explore the effect of potassium sodium dehydroandroan drographolide succinate combined with sodium thiosulfate in the treatment of eczema. Methods 80 patients with eczema were randomly allocated to the control group receiving sodium thiosulfate and the observation group receiving potassium sodium dehydroandroan dro-grapholide succinate combined with sodium thiosulfate,with 40 patients in each group. Clinical efficacy and incidence of side effect of drugs were compared between the two groups. Results Score of clinical symptoms,score of area of skin rash and total score of clinical symptom before treatment in the two groups were not statistically different （P〉0.05）.The above-mentiond score after treatment in the two groups significantly improved （P〈0.05）,and the improvement in the ob-servation group was more significant （P〈0.05）.Rash disappearing time and hospitalization time in the observation group were significantly shorter than those in the control group （P〈0.05）,and the total effective rate in the observation group was significantly higher than that in the control group （P〈0.05）.Difference of incidence rate of drug side effect between the two groups was not statistically significant （P〉0.05）. Conclusion Potassium sodium dehydroandroan drographolide succinate combined with sodium thiosulfate can significantly improve the curative effect in the treatment of eczema,and at the same time it does not increase the incidence rate of side effect of drugs.