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雷贝拉唑、克拉霉素联合阿莫西林治疗慢性胃炎的临床效果分析
引用本文:朱清芳.雷贝拉唑、克拉霉素联合阿莫西林治疗慢性胃炎的临床效果分析[J].中国当代医药,2014,0(23):106-107,110.
作者姓名:朱清芳
作者单位:朱清芳 (江西省萍乡市上栗县人民医院内二科,江西上栗,337009);
摘    要:目的:探讨雷贝拉唑、克拉霉素联合阿莫西林治疗慢性胃炎的临床效果。方法将92例慢性胃炎患者随机分为观察组和对照组,各46例,观察组给予雷贝拉唑、克拉霉素、阿莫西林治疗,对照组给予奥美拉唑、克拉霉素、阿莫西林治疗,观察两组的症状、体征及Hp根除率,并进行临床疗效评价。结果观察组Hp根除率为91.30%,高于对照组的78.26%,差异有统计学意义(P〈0.05);观察组总有效率为95.65%,高于对照组的80.43%,差异有统计学意义(P〈0.05);两组患者治疗期间均未出现相关不良反应。结论雷贝拉唑治疗慢性胃炎的临床效果优于奥美拉唑。

关 键 词:慢性胃炎  雷贝拉唑  奥美拉唑  Hp根除率

Clinical effect analysis of rabeprazole,clarithromycin combined with amoxicillin in the treatment of chronic gastritis
Authors:ZHU Qing-fang
Institution:ZHU Qing-fang;Department of Second Internal Medicine,People′s Hospital of Shangli County of Pingxiang City in Jiangxi Province;
Abstract:Objective To investigate the clinical efficacy of rabeprazole,clarithromycin combined with amoxicillin in the treatment of chronic gastritis. Methods 92 cases of patients with chronic gastritis were randomly divided into observation group and control group,46 cases of each group,rapeprazole,carithomycin and amoxicillin treatment were used in observation group,omeprazole,clarithromycin and amoxicillin treatment were used in control group.Symptoms,signs and the rate of Hp eradication in two groups was observed respectively,and the clinical efficacy was evaluated. Results Hp eradication rate in observation group was 91.30%,higher than that in control group (78.26%),with statistical difference (P〈0.05).The total effective rate in observation group was 95.65%,higher than that in control group(80.43%),with statistical difference (P〈0.05).There was no related adverse reaction occurred in the two groups of patients during treatment. Conclusion The clinical effect of chronic gastris treated by rapeprazole is better than that by omeperazole.
Keywords:Chronic gastritis  Rapeprazole  Omeprazole  Hp eradication rate
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