| 铝碳酸镁咀嚼片联合奥美拉唑治疗成人活动期胃溃疡的效果 |
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| 引用本文： | 张鹏,罗晓,梁国如.铝碳酸镁咀嚼片联合奥美拉唑治疗成人活动期胃溃疡的效果[J].中国当代医药,2014,0(23):103-105. |
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| 作者姓名： | 张鹏 罗晓 梁国如 |
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| 作者单位： | 张鹏 (广东省东莞市南城医院内科,广东东莞,523071)； 罗晓 (广东省东莞市南城医院内科,广东东莞,523071)； 梁国如 (广东省东莞市南城医院内科,广东东莞,523071)； |
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| 摘 要： | 目的：探讨铝碳酸镁咀嚼片联合奥美拉唑治疗成人活动期胃溃疡的临床效果。方法选择活动期胃溃疡成人患者120例,随机分为实验组和对照组,各60例。所有患者均给予甲硝唑400 mg/次,3次/d,克拉霉素500 mg/次,2次/d,疗程7 d；对照组给予奥美拉唑胶囊20 mg/次,2次/d；实验组给予奥美拉唑胶囊20 mg/次,3次/d,铝碳酸镁咀嚼片1000 mg/次,3次/d。治疗8周后,比较两组的溃疡面直径、溃疡愈合情况及腹痛缓解程度。结果实验组治疗后的溃疡直径为（1.52±0.12） mm,显著短于对照组的（1.75±0.14） mm（P〈0.01）。实验组的溃疡愈合率为75.00%,显著高于对照组的56.67%,差异有统计学意义（P〈0.05）。实验组的腹痛缓解率为95.00%,显著高于对照组的83.33%,差异有统计学意义（P〈0.05）。结论铝碳酸镁咀嚼片联合奥美拉唑治疗成人活动期胃溃疡的临床效果优于单用奥美拉唑。
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| 关 键 词： | 活动期胃溃疡 铝碳酸镁咀嚼片 奥美拉唑 |
Efficiency of hydrotalcite chewable tablet combined with omeprazole in the treatment of adult with active gastric ulcer |
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| Authors: | ZHANG Peng;LUO Xiao;LIANG Guo-ru |
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| Institution: | ZHANG Peng;LUO Xiao;LIANG Guo-ru;Department of Internal Medicine,Nancheng Hospital of Dongguan City in Guangdong Province; |
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| Abstract: | Objective To investigate the clinical efficiency of hydrotalcite chewable tablet combined with omeprazole in the treatment of adult with active gastric ulcer. Methods 120 cases of adult patients with active gastric ulcer were selected and randomly divided into control group（60 cases）and experimental group（60 cases）.All the patients were treated by metronidazole 400 mg/time,3 times a day,clarithromycin 500 mg/time,2 times a day,one weak as a course.Patients in control group were additionally treated with omeprazole 20 mg/time,2 times a day.Patients in experimental group were additionally treated with omeprazole 20 mg/time,3 times a day and hydrotalcite chewable tablet 1000 mg/time,3 times a day.After 8 weeks treatment,the ulcer surface diameter,ulcer healing situation,abdominal pain remission of two groups was compared respectively. Results The ulcer surface diameter in experimental group after treatment was（1.52±0.12） mm, significantly shorter than that in control group （1.75±0.14） mm]（P〈0.01）.The ulcer healing rate in experimental group was 75.00%,significantly higher than that in control group （56.67%）,with statistical difference （P〈0.05）.The abdominal pain relief rate in experimental group was 95.00%,significantly higher than that in control group（83.33%）,with statistical difference （P〈0.05）. Conclusion Clinical efficiency of hydrotalcite chewable tablet combined with omeprazole in the treatment of adult with active gastric ulcer is better than omeprazole alone. |
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| Keywords: | Active gastric ulcer Hydrotalcite chewable tablet Omeprazole |
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