原发性小肠肿瘤58例诊治分析

目的总结原发性小肠肿瘤的病理分类、临床特性及诊治经验。方法对1996年10月至2006年10月间收治的有完整资料的58例原发性小肠肿瘤病例进行回顾性分析。结果本组13例(22.4%)良性肿瘤,45例(77.6%)恶性肿瘤;其主要临床表现为消化道出血(85%)、腹痛(19%)、肠梗阻和腹部包块(16%)。术前确诊10例,胃十二指肠镜检查确诊良性肿瘤1例;另9例均为恶性肿瘤,其中选择性腹腔动脉造影发现3例,小肠镜检查发现4例,核素扫描发现2例;术前误诊率82.8%,48例为腹腔探查确诊。结论原发性小肠肿瘤恶性比例较高,缺乏特征性的临床表现及有效的诊断手段;对原因不明的腹痛、消化道出血及定位不明的腹部包块患者应及早行剖腹探查。

Diagnosis and treatment of primary tumor of small intestine:a report of 58 cases

Objective To summarize the pathological classification, clinical symptom and experience in the diagnosis and treatment of primary tumor of small intestine. Methods Data of 58 patients with primary tumor of small intestine pathologically confirmed from Oct. 1996 to Oct. 2006 were analyzed retrospectively. Results Thirteen patient (22.4%) had primary benign tumors of small intestine and 45 patient (77.6%) had primary malignant tumors of small intestine. The major clinical signs of primary tumor of small intestine included hemorrhage(85%), abdomen pain(19%), abdomen mass and intestine obstruction(16%). Forty-eight patients (82.8%) were diagnosed by laparotomy of abdominal cavity and misdiagnosed preoperatively as other diseases. Conclusions Primary tumors of small intestine are difficult to be diagnosed preoperatively. CT scan, digital subtraction angiography and radionuclide imaging are helpful for the diagnosis. Laparotomy of abdominal cavity is the main choice for those patients with suspicious tumor of small intestine.