Value of sentinel lymph node procedure in endometrial cancer |
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| Authors: | Delpech Y Coutant C Morel O Uzan S Daraï E Barranger E |
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| Affiliation: | 1. Department of Obstetrics and Gynecology and Women''s Health, Morristown and Overlook Medical Center, Atlantic Health System, Morristown, NJ 07960, USA;2. Department of Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI 48109, USA;3. Women''s Cancer Center, Carol G. Simon Cancer Center, Atlantic Health System, Morristown, NJ 07960, USA;4. Department of Clinical Pathology, Morristown Medical Center, Morristown, NJ 07960, USA;5. Division of Gynecologic Oncology, Sylvester Cancer Center, University of Miami, Miller School of Medicine, Miami, FL 33154, USA |
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| Abstract: | In cancer research, regional lymph node status is a major prognostic factor and a decision criterion for adjuvant therapy. The sentinel node procedure, which has emerged to reduce morbidity of extensive lymphadenectomy, remains a major step in the surgical management of various cancers. Sentinel node procedure has become a standard technique for the determination of the nodal stage of the disease in patients with melanoma, vulvar cancer and in breast cancer. In endometrial cancer, the sentinel node biopsy is still at the stage of feasibility. In this article, we review the technical aspects, results, clinical implications and limitations of sentinel node procedure in endometrial cancers. |
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