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帕金森病患者脑脊液中抗D2受体抗体的检测
引用本文:郭舜源,任惠民,蒋雨平,王坚. 帕金森病患者脑脊液中抗D2受体抗体的检测[J]. 中国临床神经科学, 2001, 9(2): 117-119,123
作者姓名:郭舜源  任惠民  蒋雨平  王坚
作者单位:复旦大学神经病学研究所,
基金项目:上海市科委自然科学基金资助课题(964119008)
摘    要:目的检测帕金森病(PD)患者脑脊液(CSF)中抗D2受体抗体.方法采用免疫组化和免疫印迹检测30例PD患者CSF,15例正常人CSF中的抗D2受体抗体.结果7例浓缩10倍的PD-CSF存在抗D2受体抗体,18例未浓缩PD-CSF及15例正常人CSF未检测到该抗体.结论部分PD患者CSF中存在抗D2受体抗体.

关 键 词:帕金森病 脑脊液 抗D2 受体抗体
修稿时间:2000-10-24

Investigations on Presence of Dopamine D2 Receptor Antibody in CSF of Parkinson' s Disease Patients
GUO Shun Yuan,REN Hui Min,JIANG Yu Ping,et al.. Investigations on Presence of Dopamine D2 Receptor Antibody in CSF of Parkinson' s Disease Patients[J]. Chinese Journal of Clinical Neurosciences, 2001, 9(2): 117-119,123
Authors:GUO Shun Yuan  REN Hui Min  JIANG Yu Ping  et al.
Affiliation:GUO Shun Yuan,REN Hui Min,JIANG Yu Ping,et al. Institute of Neurology,Fudan University,Shanghai 200040
Abstract:Aim:To detect an antibody of dopamine D 2 receptor in the CSF of PD patients. Methods:Dopamine D 2 receptor antibody in the CSF of 30 PD patients and 15 healthy people were studied by using immunohistochemical and immunobiochemical investigations. Results:Dopamine D 2 receptor antibody existed in 7 condensed CSF of PD patients and was not detected in 18 non condensed PD CSF and 15 condensed CSF of healthy people. Conclusion:Dopamine D 2 receptor antibody existed in the CSF from Parkinson's disease patients.
Keywords:Parkinson's disease(PD) cerebral spinal fluid (CSF) dopamine D 2 receptor antibody  
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