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透析患者脂蛋白A升高的意义
引用本文:汤金娣,徐培桢,邵智萍,尚明花,吴文俊,谢松业,陈国君,徐琴君.透析患者脂蛋白A升高的意义[J].中华器官移植杂志,1995,16(3):119-121.
作者姓名:汤金娣  徐培桢  邵智萍  尚明花  吴文俊  谢松业  陈国君  徐琴君
作者单位:上海市第一人民医院
摘    要:高脂血症是引起心血管和脑血管疾病的危险因素,为了解透析患者体内的血脂变化,测定了50例维持性血液透析(HD)和38例连续非卧床腹膜透析(CAPD)患者及50例正常人的脂蛋白A[Lp(a)]及其他血脂。结果HD组及CAPD组的Lp(a)均显著高于对照组(P<0.01),两组患者的甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、载脂蛋白AI/载脂蛋白B、载脂蛋白AI、载脂蛋白B均有异常。两组患者Lp(a)的升高与其他异常血脂之间无相关性。35例非糖尿病CAPD者Lp(a)升高与空腹血糖、血浆白蛋白无相关性。结果提示透析患者动脉粥样硬化的危险性可能增加。

关 键 词:脂蛋白A  血脂过多  血液透析  腹膜透析

Studies on elevated lipoprotein levels in dialysis patients
Tang Jinde, Xu Peizhen, Shao Zhiping,et al..Studies on elevated lipoprotein levels in dialysis patients[J].Chinese Journal of Organ Transplantation,1995,16(3):119-121.
Authors:Tang Jinde  Xu Peizhen  Shao Zhiping  
Institution:Tang Jinde, Xu Peizhen, Shao Zhiping, et al.
Abstract:Plasma lipoprotein A Lp (a)] levels and other lipoproteins in 50 patients on HD, 38 patients on CAPD and 50 normal controls were tested. Lp(a) in the CAPD and HD groups were obviously higher than that of control group (P<0. 01). Abnormal serum TG . HDL-ch,LDL-ch, apo AI, apo b and apo AI/apo B levels were also observed in 2 dialysis groups. No significant correlation between Lp(a) and other lipid constituents showed.There were no correlation between serum Lp(a) level and albumin or serum glucose in non-diabetic CAPD patients.The risk and machnism of hyperlipidemia in dialysis patients are discussed.
Keywords:Lipoprotein A Hyperlipidemia hemo Dialysis Continuous ambulatory poritoneal dialysis
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