| 持续吸入氟替卡松对哮喘儿童肺功能的改善及安全性评价 |
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| 引用本文： | 范楚平,张碧清,张彤如,刘佳. 持续吸入氟替卡松对哮喘儿童肺功能的改善及安全性评价[J]. 医学理论与实践, 2009, 22(12): 1413-1414 |
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| 作者姓名： | 范楚平 张碧清 张彤如 刘佳 |
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| 作者单位： | 南方医科大学附属郴州市第一人民医院儿童内科一区,湖南省郴州市,423000 |
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| 基金项目： | 湖南省卫生厅资助项目B2008-096;郴州市科技局资助项目2008-109 |
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| 摘 要： | 目的:探讨持续雾化吸入氟替卡松对哮喘儿童肺功能的改善及安全性。方法:选择95例6~48个月的哮喘患儿持续(6个月)吸入氟替卡松,每日100μg,Bid。治疗前及治疗6个月后分别测定各项肺功能指标、血皮质醇及骨密度。结果:治疗6个月后,肺功能有明显改善,血皮质醇及骨密度无明显变化。结论:吸入氟替卡松气雾剂每日100μg,Bid,6个月后,能改善哮喘患儿肺功能,降低气道高反应性,对患儿肾上皮质功能及骨密度未见显著影响。
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| 关 键 词： | 婴幼儿 支气管哮喘 雾化吸入 氟替卡松 肺功能 血皮质醇 骨密度 |
Safety Evaluation of Children with Asthma and Improvement in Inhalation Fluticasone Continued |
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| Affiliation: | FAN Chuping, ZHANG Biqing, ZHA.NG Tongru, et al.( The First Ward, Department of Pediatrics, the First People ＇ s Hospital of Chenzhou City, South of Medical University, Hu nan Province 423000) |
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| Abstract: | Objective：To investigate the safety and improvement young children with asthma inhalation fluticasone continued.Methods：We selected 95 cases children with asthma and the age were between 648 months.The patients were inhalated fluticasone for 6 months,100μg,Bid.We detected the pulmonary function,hydrocortisone in blood plasm and bone density.Results：After accept the treatment for 6 months the pulmonary function were improved obviously and the hydrocortisone in blood plasm and bone density did not make change.Conclusion：In inhalation fluticasone continued for 6 months,100μg,Bid can improve the children＇s pulmonary function,decrease airway hyperreactivity and do not influence hydrocortisone and bone density. |
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| Keywords: | Young children Bronchial asthma Inhalation Fluticasone Pulmonary function Hydrocortisone in blood plasm Bone density |
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