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Plasma somatomedin-C levels in psoriasis
Authors:B.J. NICKOLOFF  PRATIMA MISRA  VERA B. MORHENN  R.L. HINTZ  R.G. ROSENFELD
Affiliation:Departments of Dermatology, Stanford University School of Medicine, Stanford, California, U.S.A.;Departments of Pediatrics, Stanford University School of Medicine, Stanford, California, U.S.A.
Abstract:We have measured plasma levels of somatomedin-C, one of the principal mediators of growth hormone action, in 25 patients with plaque-type psoriasis of varying severity and compared these levels with those found in healthy controls. Plasma somatomedin-C levels were not elevated in the psoriatic patients regardless of the severity of their disease, suggesting that in these patients growth hormone secretion is within normal limits.
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