| 血必净联合血液净化治疗严重脓毒症临床研究 |
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| 引用本文： | 赵淑杰,张东,李洪祥,陈颖,王育珊. 血必净联合血液净化治疗严重脓毒症临床研究[J]. 实用诊断与治疗杂志, 2010, 24(4) |
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| 作者姓名： | 赵淑杰 张东 李洪祥 陈颖 王育珊 |
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| 作者单位： | 吉林大学第二临床学院ICU科,长春市,130051 |
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| 摘 要： | 目的:探讨血必净联合血液净化治疗严重脓毒症的临床疗效。方法:将84例严重脓毒症患者分为A组(常规治疗组)26例、B组(常规治疗+血必净组)20例、C组(常规治疗+血液净化组)22例、D组(常规治疗+血必净+血液净化组)16例,观察各组治疗前及治疗后24,48,72 h血小板计数、凝血酶原时间、活化部分凝血酶时间、纤维蛋白原、血肌酐、尿素氮、尿量以及氧合指数、APACHEⅡ评分,比较各组多器官功能障碍综合征的发生率。结果:治疗后4组血小板计数、凝血酶原时间、活化部分凝血酶时间、纤维蛋白原、尿量、血肌酐、尿素氮、氧合指数较治疗前均有改善(P<0.05),但B,C,D组改善明显,D组疗效更显著(P<0.01);治疗后APACHEⅡ评分及多器官功能障碍综合征发生率明显下降,D组下降更明显(P<0.01)。结论:血必净联合血液净化治疗严重脓毒症可预防多器官功能障碍综合征的发生,降低病死率。
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| 关 键 词： | 严重脓毒症 血必净 血液净化 |
Clinical study on Xuebijing injection combined with blood purification for severe sepsis |
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| ZHAO Shujie,ZHANG Dong,LI Hongxiang,et al.. Clinical study on Xuebijing injection combined with blood purification for severe sepsis[J]. Journal of Practical Diagnosis and Therapy, 2010, 24(4) |
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| Authors: | ZHAO Shujie ZHANG Dong LI Hongxiang et al. |
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| Affiliation: | ZHAO Shujie,ZHANG Dong,LI Hongxiang,et al.ICU,the Second Affiliated Hospital to Jilin University,Changchun 130051,China |
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| Abstract: | Objective To explore the therapeutic effect of Xuebijing injection combined with blood purification on severe sepsis.Methods Eight-four patients with severe sepsis were randomly divided into group A(n=26,conventional therapy),group B(n=20,conventional therapy plus Xuebijing),group C(n=22,conventional therapy plus blood purification),and group D(n=18,conventional therapy plus Xuebijing and blood purification).The different levels of blood platelet count,thromboplastin time,activated partial thromboplastin ti... |
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| Keywords: | Severe sepsis Xuebijing injection blood purification |
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